一、簡(jiǎn)介:
農(nóng)藥凍融穩(wěn)定性試驗(yàn)箱依據(jù)NYT 2989-2016 農(nóng)藥登記產(chǎn)品規(guī)格制定規(guī)范設(shè)計(jì)制造。用于微囊液體制劑的凍融穩(wěn)定性試驗(yàn),壓縮機(jī)、加熱部分、電源控制部分均采用進(jìn)口件,高質(zhì)量、高性能。滿(mǎn)載運(yùn)轉(zhuǎn)時(shí)凍融箱內(nèi)各點(diǎn)溫度極差不超過(guò)1℃。自動(dòng)控制,數(shù)據(jù)曲線(xiàn)實(shí)時(shí)動(dòng)態(tài)顯示、試驗(yàn)數(shù)據(jù)自動(dòng)存儲(chǔ),具有試驗(yàn)意外終止自動(dòng)恢復(fù)功能。
微囊液體制劑等應(yīng)進(jìn)行凍融穩(wěn)定性試驗(yàn)。試驗(yàn)?zāi)康氖谴_保成囊制劑在溫度變化時(shí)囊的完整性,以確保有效成分完整的釋放。結(jié)凍和融化穩(wěn)定性試驗(yàn)條件為在(-10±2)℃和(20±2)℃之間做4個(gè)循環(huán),每個(gè)循環(huán)為結(jié)凍18h融化6h。微囊液體制劑主要有微囊懸浮劑(CS)、微囊懸浮-水乳劑(ZW)、微囊懸浮-懸浮劑(ZC)、微囊懸浮-懸乳劑(ZE)等劑型。
1.微囊懸浮劑(CS)及微囊懸浮-懸浮劑(ZC)凍融穩(wěn)定性合格要求為:儲(chǔ)后游離有效成分含量、酸堿度或pH范圍、濕篩試驗(yàn)、懸浮率、自發(fā)分散性、傾倒性等應(yīng)符合產(chǎn)品規(guī)格要求;
2.微囊懸浮-水乳劑(ZW)及微囊懸浮-懸乳劑(ZE)凍融穩(wěn)定性合格要求為:儲(chǔ)后游離有效成分含量、酸堿度或pH范圍、濕篩試驗(yàn)、分散穩(wěn)定性、傾倒性等應(yīng)符合產(chǎn)品規(guī)格要求。
1. Introduction
The pesticide freeze-thaw stability test chamber is designed and manufactured in accordance with NYT 2989-2016 pesticide registration product specifications. It is used for freeze-thaw stability test of microcapsule liquid preparations. The compressor, heating part and power control part are all imported parts with high quality and high performance. The temperature difference of each point in the freezing and thawing box does not exceed 1℃ when operating at full load. Automatic control, real-time dynamic display of data curve, automatic storage of test data, and automatic recovery function for unexpected termination of test.
Freeze-thaw stability tests should be carried out for microencapsulated liquid preparations. The purpose of the test is to ensure the integrity of the capsule when the temperature changes in the encapsulated formulation, so as to ensure the complete release of the active ingredients. The freezing and thawing stability test conditions are 4 cycles between (-10±2)℃ and (20±2)℃, and each cycle is freezing for 18h and thawing for 6h. Microcapsule liquid preparations mainly include microcapsule suspension (CS), microcapsule suspension-water emulsion (ZW), microcapsule suspension-suspension (ZC), microcapsule suspension-suspension emulsion (ZE) and other dosage forms.
1. Qualified requirements for freeze-thaw stability of microcapsule suspension (CS) and microcapsule suspension-suspension (ZC) are: free active ingredient content after storage, pH or pH range, wet sieve test, suspension rate, spontaneous dispersion, Pourability, etc. should meet product specifications;
2. Qualified requirements for freeze-thaw stability of microcapsule suspension-water emulsion (ZW) and microcapsule suspension-suspoemulsion (ZE) are: free active ingredient content after storage, pH or pH range, wet sieve test, dispersion stability, dumping The performance should meet the product specification requirements.
二、技術(shù)參數(shù):
1、有效容積:500×500×600mm
2、外形尺寸:1350×850×1700mm
3、溫度范圍:-40℃~+80℃
4、升降溫速率:升溫速率:3℃/min
5、降溫速率:0.7~1℃/min(+80℃<->-40℃??蛰d,全程平均)->
6、循環(huán)次數(shù):4次(任意設(shè)定)
7、凍結(jié)時(shí)間:18小時(shí)(任意設(shè)定)
8、融化時(shí)間:6小時(shí)(任意設(shè)定)
9、溫度波動(dòng)度:≤±0.5℃
10、溫度均勻度:≤2℃
11、溫度偏差:≤±2℃
12、運(yùn)行功率:≈3.0KW
13、凈重:150KG
2. Technical parameters
1. Effective volume: 500×500×600mm
2. Dimension: 1350 × 850 × 1700mm
3. Temperature range: -40℃~+80℃
4, ramp rate: heating rate: 3 ℃ / min
5. Cooling rate: 0.7~1℃/min (+80℃<->-40℃. No load, average throughout the whole process)->
6. Number of cycles: 4 times (arbitrarily set)
7. Freezing time: 18 hours (arbitrarily set)
8. Melting time: 6 hours (arbitrarily set)
9. Temperature fluctuation: ≤±0.5℃
10. Temperature uniformity: ≤2℃
11. Temperature deviation: ≤±2℃
12. Operating power: ≈3.0KW
13. Net weight: 150KG
三、主機(jī)配置:
1、7寸TFT真彩液晶、可編程溫度控制儀
2、制冷壓縮機(jī):法國(guó)泰康全封閉風(fēng)冷,
3、PLC主模塊、溫度傳感器模塊、通訊線(xiàn)、以太網(wǎng)/USB延長(zhǎng)、配件包
4、支持USB接口連接移動(dòng)U盤(pán)導(dǎo)出歷史曲線(xiàn)、歷史數(shù)據(jù)、報(bào)警記錄,可用PC上位機(jī)軟件打開(kāi) U盤(pán)中導(dǎo)出的數(shù)據(jù)進(jìn)行查看、打印、記錄
5、遠(yuǎn)程控制
A電腦安裝上位機(jī)監(jiān)控軟件通過(guò)以太網(wǎng)口直連或者無(wú)線(xiàn)路器由局域網(wǎng)進(jìn)行遠(yuǎn)程監(jiān)控:
6、接口功能:接口設(shè)備支持微型打印機(jī)
7、運(yùn)行模式:定值、程式運(yùn)行可以選擇
8、溫濕度精度顯示調(diào)節(jié)
9、屏保、亮度可調(diào)功能
10、超溫、報(bào)警停機(jī)功能
11、溫度多點(diǎn)補(bǔ)償功能
12、 工作室:304不銹鋼板
13、外殼:優(yōu)質(zhì)冷板表面噴塑
14、帶觀(guān)察窗照明燈
Three, host configuration:
1. 7-inch TFT true color LCD, programmable temperature controller
2. Refrigeration compressor: French Taikang fully enclosed air-cooled,
3. PLC main module, temperature sensor module, communication line, Ethernet/USB extension, accessory package
4. Support the USB interface to connect to the mobile U disk to export historical curves, historical data, and alarm records. You can open the exported data in the U disk with the PC host computer software to view, print, and record
5. Remote control
A computer installs the host computer monitoring software through the Ethernet port direct connection or the wireless router is remotely monitored by the local area network:
6. Interface function: The interface device supports micro printers
7. Operation mode: fixed value and program operation can be selected
8. Temperature and humidity accuracy display adjustment
9. Screen saver and brightness adjustable function
10. Over temperature, alarm and shutdown function
11. Temperature multi-point compensation function
12. Studio: 304 stainless steel plate
13. Shell: high-quality cold plate with plastic spray on the surface
14. Lighting lamp with observation window