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產(chǎn)品名稱 | 英文名稱 | 包裝 |
溶壁微球菌細胞使用說明書 | Micrococcus lysodeikticus cells | 可根據(jù)客戶要求訂制 |
溶壁微球菌細胞使用說明書分子生物學領(lǐng)域:
涉及核酸純化、常用分子生物學試劑、PCR等相關(guān)試劑盒。
分子生物學試劑:擁有的價格優(yōu)勢,品質(zhì)可信賴,市場占比龐大。
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147-71-7 20mg D(-)-Tartaric acid D-酒石酸
87-69-4 20mg L(+)-Tartaric acid L-酒石酸
10482-56-1 20mg α-Terpineol α-松油醇
4180-23-8 20mg Trans-Anethole 反式茴香腦
51-67-2 20mg Tyramine 對羥基苯乙胺-酪胺
63903-51-5 20mg Zinc Phytate 植酸鋅
30252-40-5 100mg Potassium 7-hydroxynaphthalene-1-sulfonate 2-萘酚-8-磺酸鉀
10323-20-3 100mg D-arabinose D-阿拉伯糖
87-72-9 100mg L-arabinose L-阿拉伯糖
56180-94-0 20mg Acarbose 阿卡波糖
488-81-3 20mg Adonitol D-阿拉伯糖醇
34620-76-3 10mg Amylopentaose 麥芽五糖
22839-47-0 250mg Aspartame 阿斯巴甜
577-76-4 10mg Chitobiose 2HCl 殼二糖
10mg Chitotriose 3HCl 殼三糖
41708-93-4 10mg Chitotetraose 4HCl 殼四糖
35061-50-7 10mg Chitopentaose 5HCl 殼五糖
human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Component of the MRE11/RAD50/NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of omere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in omere length maintenance by generating the 3' overhang which serves as a primer for omerase dependent omere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability.
Function : Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA 溶壁微球菌細胞使用說明書recombination, maintenance of omere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA