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腫瘤細(xì)胞檢測(cè)靶點(diǎn)

時(shí)間:2018/9/7閱讀:429
分享:
MARKERN-1N-3N-4N-6N-7N-8N-11N-20/1N-20/2N-25/2N-25/3N-29/1N-29/2N-29/3N-29/4N-36/1N-36/2N-37N-38N-39
Adiponectin receptor 1N/ART- bad
Adiponectin receptor 2N/ART- bad
Adiponutrin (cDNA)---weakN/Aweakweak?weakweak----
Adiponutrin (one-step)weak-N/Aweakweakweakweakweakweakweak
Agrp-
AhR++N/A++
Angiotensinogenstrongstrongstrongstrongstrongstrongstrongstrongstrongweak+weakweakweakstrongstrongstrongweak ?strong
Angiotension Receptor 1strongstrong-weakstrongN/Aweak weak-+-strong---weak--strong
Angiotension Receptor 2  weak   strong strong     strong  strongstrongstrong
AR-weak-weak-weak-weak-weak--N/A--
Arnt2
Aromatase+---weak-----N/A----N/A---+
Avp-------+weak  +     +--
AVPR1aN/AN/Aweakweakweak
AVPR1bweakN/Aweak
BDNFN/AweakN/Aweakweakweak
BRS-3+       +       +   
Calcium Receptor (CaR)weakN/A-strong--strongstrong--
CARTweakN/Aweakweak------weak-weak
CB1 receptor--N/A----N/A--N/A-N/AN/A--N/AN/AN/A
cc1αb                   
cc1αc                  
ChATN/A-N/AN/AN/AN/AN/Aweakweak----N/A-N/A--
chemerinweakweak?N/A?-weak-
chemerinRN/Aweakweak
CNTFRN/Aweakweakweakweak--
CRFR1weak-weakweakN/A-N/AweakN/A-weakweak
CRFR2---N/Aweak----
CRH/CRF---weak---------------weak
CRLRN/AN/AN/AN/AN/AN/AN/A-----N/A-
DATweakstrong-------
Dpp4----N/A---------weak----
Dynorphin-----N/A----N/A---------
ER α--weak--weak
ER β
FIAFN/A
Gad 1 (Gad 67)N/A-
Gad 2 (Gad 65)----?-?--?-
Gal--weak-----------
GALP------N/AN/A--------
GCKN/AN/AN/AN/AN/AN/AN/AN/AN/A
GFAP-------          N/A- 
Ghrelin N/AN/A------
Ghrelin variant-N/AN/A------weak--
GHRH (southern)weak--weakweak  weak       
GHSR1a++++weak +weakweakstrong ++-++weakstrongweak+
Glp1R-strongstrongN/Aweak---N/A-----
Glp2R--strong-strongN/A----N/A--------strong
Glucagon receptor?N/A------------
Glucocorticoid  receptor (GR)
GLUT1
GLUT2------weak--------
GLUT3weakweakweak
GLUT4
GLUT5strong                   
GMR alphaweak---N/A??
GnIH (Rfrp)????N/A-?---weakstrong
GnRH+ weak ++strong +   weak-  
GnRH Receptor-------    -     -- 
Gpr 39N/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/A
Gpr 120-strong-weakweakN/A----N/Astrongweak-weak--weak-strong
Grp--weakweakweakN/Aweak-----weak-strong
GrpRN/Aweakweakweakweakweakweak
Ht1b (5-Ht1b)  N/A
Htr2a (5-Htr2a)  -weakweakweak
Htr2c-----N/A--------------
IGF
IGF1R
IGFBP-1----N/A---------------
IL-1 Beta  - ++       weak      
Insulin I-------N/A------------
Insulin II------N/Aweakweak--------
Insulin ReceptorN/AN/AN/AN/AN/AN/AN/A
Insulin receptor substrate 2N/A----
Kir6.1N/A-N/AN/AN/AN/AN/A--------N/A-N/A--
Kir6.2N/AN/AN/AN/AN/AN/AN/A--?-???N/A-
Kisspeptin-+N/Aweak--weak------weak--
Kiss Receptor (GPR54)N/A
Lep Receptorweakweak--weak--+
Lipoprotein lipase (LPL)+-weak                 
mc3R+-+                 
mc4RN/AN/AN/AN/AN/AN/A+-------N/A-+
MCHN/AN/AN/AN/Aweak
MCHR1weakweakweakN/Aweak
New-1-------          -- 
New-2-------          -- 
New-4-          - 
NMS (no.3)                    
Nmuweak---weak-weak-weak---
NPBN/Aweak
NPWweak-NAweakweakweakweakweakweakweakweakweak-weak
NPYvery weak-----weak--very weakweak---------
NPY-Y1       N/AN/AN/AN/AN/AN/AN/AN/A 
NPY-Y2       N/AN/AN/AN/AN/AN/AN/AN/A 
NPY-Y4       N/AN/AN/AN/AN/AN/AN/AN/A 
NPY-Y5       N/AN/AN/AN/AN/AN/AN/A-N/A -
NSE           
NT--------strong--
NTR1-N/AN/A--weak--weak---weakweak-
OprlRN/A-
orexin--------------------
orexin R1N/A-weak
orexin R2??-N/A--weak---
Oxytocin    ---           weak 
pAdcyap1----?-----------
POMC                     
proGlu---weak------------weak
proGlu (2007)---N/A----N/A----weak-weak-strong
PTH2-Rweak-N/Aweak-weakweakweakweakweak-weakweakweakweakN/A--weak
resistinN/A--?N/A--weak
SecretinstrongstrongN/Aweak?--------weak---
5-HT7 receptorstrong  strongstrongstrongstrong strong    strong    strong 
SF-1N/A
Sim1 (S1)not clearnot clear-strongvery weak -weak-strongstrong-strongstrongweakweakstrongstrongstrong
Socs-3-
somatostatin (som)-weakN/A?--????weak
SSTY          - --
STAT3N/AN/A
STATN/AN/A
STAT5BN/AN/A
Sur1N/A-N/AN/AN/AN/AN/A--weak-weak---N/A-N/A--
Sur2N/A-N/AN/AN/AN/AN/A--------N/A-N/A-
Syndecan 3strongstrongstrongstrongstrongN/Astrongstrongstrongstrongstrongstrongstrongstrongstrongstrongstrongstrongstrongstrong
T antigen
TAC2 (neurokinin B)?weak--strong-weakweak----weakweak---?-weak
TH-weak-weakweak--weak----
Tph------          strongweak 
THRalpha        ++          
THRbeta        ++          
TRH----N/A---------------
Ucnweakweak----
Ucp2N/A
VGFN/Aweakweakweakweak
VIP-strong-strongN/AweakweakN/AN/Astrongweakstrongstrong
VIPR1weakN/A-weak-------?weak-
VIPR2N/Aweakweak
MARKERN-1N-3N-4N-6N-7N-8N-11N-20/1N-20/2N-25/2N-25/3N-29/1N-29/2N-29/3N-29/4N-36/1N-36/2N-37N-38N-39
Adiponectin receptor 1N/ART- bad
Adiponectin receptor 2N/ART- bad
Adiponutrin (cDNA)---weakN/Aweakweak?weakweak----
Adiponutrin (one-step)weak-N/Aweakweakweakweakweakweakweak
Agrp-
AhR++N/A++
Angiotensinogenstrongstrongstrongstrongstrongstrongstrongstrongstrongweak+weakweakweakstrongstrongstrongweak ?strong
Angiotension Receptor 1strongstrong-weakstrongN/Aweak weak-+-strong---weak--strong
Angiotension Receptor 2  weak   strong strong     strong  strongstrongstrong
AR-weak-weak-weak-weak-weak--N/A--
Arnt2
Aromatase+---weak-----N/A----N/A---+
Avp-------+weak  +     +--
AVPR1aN/AN/Aweakweakweak
AVPR1bweakN/Aweak
BDNFN/AweakN/Aweakweakweak
BRS-3+       +       +   
Calcium Receptor (CaR)weakN/A-strong--strongstrong--
CARTweakN/Aweakweak------weak-weak
CB1 receptor--N/A----N/A--N/A-N/AN/A--N/AN/AN/A
cc1αb                   
cc1αc                  
ChATN/A-N/AN/AN/AN/AN/Aweakweak----N/A-N/A--
chemerinweakweak?N/A?-weak-
chemerinRN/Aweakweak
CNTFRN/Aweakweakweakweak--
CRFR1weak-weakweakN/A-N/AweakN/A-weakweak
CRFR2---N/Aweak----
CRH/CRF---weak---------------weak
CRLRN/AN/AN/AN/AN/AN/AN/A-----N/A-
DATweakstrong-------
Dpp4----N/A---------weak----
Dynorphin-----N/A----N/A---------
ER α--weak--weak
ER β
FIAFN/A
Gad 1 (Gad 67)N/A-
Gad 2 (Gad 65)----?-?--?-
Gal--weak-----------
GALP------N/AN/A--------
GCKN/AN/AN/AN/AN/AN/AN/AN/AN/A
GFAP-------          N/A- 
Ghrelin N/AN/A------
Ghrelin variant-N/AN/A------weak--
GHRH (southern)weak--weakweak  weak       
GHSR1a++++weak +weakweakstrong ++-++weakstrongweak+
Glp1R-strongstrongN/Aweak---N/A-----
Glp2R--strong-strongN/A----N/A--------strong
Glucagon receptor?N/A------------
Glucocorticoid  receptor (GR)
GLUT1
GLUT2------weak--------
GLUT3weakweakweak
GLUT4
GLUT5strong                   
GMR alphaweak---N/A??
GnIH (Rfrp)????N/A-?---weakstrong
GnRH+ weak ++strong +   weak-  
GnRH Receptor-------    -     -- 
Gpr 39N/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/A
Gpr 120-strong-weakweakN/A----N/Astrongweak-weak--weak-strong
Grp--weakweakweakN/Aweak-----weak-strong
GrpRN/Aweakweakweakweakweakweak
Ht1b (5-Ht1b)  N/A
Htr2a (5-Htr2a)  -weakweakweak
Htr2c-----N/A--------------
IGF
IGF1R
IGFBP-1----N/A---------------
IL-1 Beta  - ++       weak      
Insulin I-------N/A------------
Insulin II------N/Aweakweak--------
Insulin ReceptorN/AN/AN/AN/AN/AN/AN/A
Insulin receptor substrate 2N/A----
Kir6.1N/A-N/AN/AN/AN/AN/A--------N/A-N/A--
Kir6.2N/AN/AN/AN/AN/AN/AN/A--?-???N/A-
Kisspeptin-+N/Aweak--weak------weak--
Kiss Receptor (GPR54)N/A
Lep Receptorweakweak--weak--+
Lipoprotein lipase (LPL)+-weak                 
mc3R+-+                 
mc4RN/AN/AN/AN/AN/AN/A+-------N/A-+
MCHN/AN/AN/AN/Aweak
MCHR1weakweakweakN/Aweak
New-1-------          -- 
New-2-------          -- 
New-4-          - 
NMS (no.3)                    
Nmuweak---weak-weak-weak---
NPBN/Aweak
NPWweak-NAweakweakweakweakweakweakweakweakweak-weak
NPYvery weak-----weak--very weakweak---------
NPY-Y1       N/AN/AN/AN/AN/AN/AN/AN/A 
NPY-Y2       N/AN/AN/AN/AN/AN/AN/AN/A 
NPY-Y4       N/AN/AN/AN/AN/AN/AN/AN/A 
NPY-Y5       N/AN/AN/AN/AN/AN/AN/A-N/A -
NSE           
NT--------strong--
NTR1-N/AN/A--weak--weak---weakweak-
OprlRN/A-
orexin--------------------
orexin R1N/A-weak
orexin R2??-N/A--weak---
Oxytocin    ---           weak 
pAdcyap1----?-----------
POMC                     
proGlu---weak------------weak
proGlu (2007)---N/A----N/A----weak-weak-strong
PTH2-Rweak-N/Aweak-weakweakweakweakweak-weakweakweakweakN/A--weak
resistinN/A--?N/A--weak
SecretinstrongstrongN/Aweak?--------weak---
5-HT7 receptorstrong  strongstrongstrongstrong strong    strong    strong 
SF-1N/A
Sim1 (S1)not clearnot clear-strongvery weak -weak-strongstrong-strongstrongweakweakstrongstrongstrong
Socs-3-
somatostatin (som)-weakN/A?--????weak
SSTY          - --
STAT3N/AN/A
STATN/AN/A
STAT5BN/AN/A
Sur1N/A-N/AN/AN/AN/AN/A--weak-weak---N/A-N/A--
Sur2N/A-N/AN/AN/AN/AN/A--------N/A-N/A-
Syndecan 3strongstrongstrongstrongstrongN/Astrongstrongstrongstrongstrongstrongstrongstrongstrongstrongstrongstrongstrongstrong
T antigen
TAC2 (neurokinin B)?weak--strong-weakweak----weakweak---?-weak
TH-weak-weakweak--weak----
Tph------          strongweak 
THRalpha        ++          
THRbeta        ++          
TRH----N/A---------------
Ucnweakweak----
Ucp2N/A
VGFN/Aweakweakweakweak
VIP-strong-strongN/AweakweakN/AN/Astrongweakstrongstrong
VIPR1weakN/A-weak-------?weak-
VIPR2N/Aweakweak

 

MARKERN-40N-41N-42N-43N-44N-45N-46N-47GT1-7HypothalamusMin6MOVASGnV3GnV4
Adiponectin receptor 1N/AN/A    
Adiponectin receptor 2N/AN/A    
Adiponutrin (cDNA)N/AweakN/Aweakweak    
Adiponutrin (one-step)N/A-weak    
Agrp    
AhR43/5 + weak    
Angiotensinogenweakstrongweakweakweak ?weakstrongN/AN/AN/A  
Angiotension Receptor 1strongstrongweak43/5 -strongstrongweakN/AstrongN/AN/AN/A--
Angiotension Receptor 2weak--43/5 --weakweakN/A-N/AN/AN/A--
AR    
Arnt243/5 +     
Aromatase+++43/5 ---N/A+-N/AN/A
Avp-- 43/5 ----+    
AVPR1a43/5 + weakN/AN/A  
AVPR1b43/5 + weak-N/AN/A  
BDNFN/A43/5 + weakN/AN/A  
BRS-3  -   -       
Calcium Receptor (CaR)strong-43/5 + --strongstrong    
CARTweak?-43/5 + weakweakweakweakN/AN/A  
CB1 receptorN/AN/AN/AN/Aweak    
cc1αb           
cc1αc           
ChAT--weak--weak-    
chemerin43/5 weak ?N/AN/A  
chemerinRN/A43/5 + N/AN/AN/A  
CNTFR43/5 + N/AN/A
CRFR143/5 -strongN/A-N/AN/Astrong   
CRFR2-43/5 + -N/Astrongstrong   
CRH(idt)-weakweak43/5 weak weak----strong    
CRLR-    
DAT-    
Dpp4---43/5 ---    
Dynorphin---43/5 ----N/AN/A    
ER αN/AN/AN/AN/A
ER β    
FIAFN/A    
Gad 1 (Gad 67)N/A    
Gad 2 (Gad 65)N/A?    
Gal-    
GALP-43/5 --N/A--N/AN/AN/AN/AN/A
GCKN/A    
GFAP        -+    
Ghrelin ---    
Ghrelin variant----    
GHRH (southern) weak   weak     
GHSR1a+ strongstrongweakstrong++n/a+     
Glp1R-+-43/5 ----N/AstrongstrongN/AN/A--
Glp2R-weak-43/5 ----N/A-strongN/AN/A--
Glucagon receptor43/5 weak weak-weakN/AN/A--
Glucocorticoid  receptor (GR)N/A43/5 + N/A    
GLUT1    
GLUT2-43/5 ---strong    
GLUT3    
GLUT4    
               
GMR alpha43/5 + weakN/AN/A--
GnIH (Rfrp)strong43/5 + -strongstrongstrongN/AN/A  
GnRH+very weak  strong-+weakN/A    
GnRH Receptor-       -    
Gpr 39?43/5 + N/AN/A-very weak?N/AN/A--
Gpr 120weakweak-43/5 ----N/A-strongN/AN/A--
Grp--43/5 -weakN/A-weakstrongstrong-   
GrpR43/5 + N/AN/A  
Ht1b (5-Ht1b)  +++43/5 + N/AN/AN/A--
Htr2a (5-Htr2a)  N/A43/5 + N/A-    
Htr2c---43/5 ----N/AstrongstrongN/AN/A--
IGF43/5 + N/AN/AN/AN/A
IGF1R43/5 + N/AN/AN/AN/A
IGFBP-1---43/5 ------weakN/AN/A--
IL-1 Beta     -        
Insulin I---43/5 --N/A--N/A?strong   
Insulin II---43/5 --N/A+-N/Astrong   
Insulin Receptor    
Insulin receptor substrate 2    
Kir6.1---------    
Kir6.2N/A?---    
Kiss--------    
Kiss ReceptorN/A    
Lep Receptorweak-weak    
Lipoprotein lipase (LPL) strong+ +         
mc3R -- +         
mc4R-?    
MCH    
MCHR1    
New-1        -    
New-2        weak    
New-4            
NMS (no.3)          strong   
NmuN/A-    
NPB++weak43/5 + N/AN/AN/A
NPW+++43/5 + weakweakN/A-N/AN/A--
NPY-----weak/+--    
NPY-Y1N/AN/AN/AN/AN/AN/AN/A-    
NPY-Y2N/AN/AN/AN/AN/AN/AN/A    
NPY-Y4N/AN/AN/AN/AN/AN/AN/A    
NPY-Y5N/AN/AN/AN/AN/AN/AN/A-    
NSE        N/A    
NT    
NTR1---weak-----    
OprlR43/5 + weakN/AN/A--
orexin---------    
orexin R1weak43/5 + weakN/AN/A?-
orexin R243/5 --N/AN/A
Oxytocin            
pAdcyap1--43/5 weak ---weak-N/A   
POMC        N/AN/A    
proGlu------    
proGlu (2007)--weak43/5 weak---N/AstrongN/A--
PTH2-Rweakweakweakweak----    
resistinN/Aweak-weak    
Secretin-strong+43/5 weakweak--N/A-+N/AN/A--
5-HT7 receptorstrong             
SF-143/5 +     
Sim1 (S1)-43/5 strong weakstrongstrong    
Socs-3    
somatostatin (som)?weak??N/Aweak?strongstrong   
SSTY 43/5 -   --  
STAT3    
STATweak    
STAT5B    
Sur1---    
Sur2weakweakweak--    
Syndecan 3strongstrongstrong43/5 strong strongstrongstrongN/AstrongN/AN/A
T antigenN/A    
TAC2 (neurokinin B)-weakweak43/5 --strongweakstrongN/AN/AN/A
TH-43/5 + --    
Tph        N/A    
THRalpha   +          
THRbeta   +          
TRH---43/5 -----    
Ucnweakweakweak    
Ucp243/5 + N/AN/A
VGF43/5 + N/AN/A  
VIPstrong43/5 weak -N/AN/Astrongweak   
VIPR1-43/5 + -weak-N/AN/A  
VIPR243/5 + weakN/AN/A  

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