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當(dāng)前位置:北京百奧創(chuàng)新科技有限公司>>技術(shù)文章>>腫瘤細(xì)胞檢測(cè)靶點(diǎn)
MARKER | N-1 | N-3 | N-4 | N-6 | N-7 | N-8 | N-11 | N-20/1 | N-20/2 | N-25/2 | N-25/3 | N-29/1 | N-29/2 | N-29/3 | N-29/4 | N-36/1 | N-36/2 | N-37 | N-38 | N-39 |
Adiponectin receptor 1 | + | + | + | + | + | N/A | RT- bad | + | + | + | + | + | + | + | + | + | + | + | + | + |
Adiponectin receptor 2 | + | + | + | + | + | N/A | RT- bad | + | + | + | + | + | + | + | + | + | + | + | + | + |
Adiponutrin (cDNA) | - | - | - | weak | + | N/A | weak | + | weak | + | ? | + | weak | weak | + | + | - | - | - | - |
Adiponutrin (one-step) | weak | - | + | + | + | N/A | + | + | weak | + | weak | + | weak | + | + | + | weak | weak | weak | weak |
Agrp | + | + | + | + | + | + | + | + | + | + | + | + | + | + | - | + | + | + | + | + |
AhR | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Angiotensinogen | strong | strong | strong | strong | strong | strong | strong | strong | strong | weak | + | + | weak | weak | weak | strong | strong | strong | weak ? | strong |
Angiotension Receptor 1 | strong | strong | - | weak | strong | N/A | weak | weak | - | + | - | strong | - | - | - | weak | - | - | strong | |
Angiotension Receptor 2 | weak | strong | strong | strong | strong | strong | strong | |||||||||||||
AR | - | + | weak | + | - | weak | - | + | + | weak | - | weak | - | weak | - | - | + | N/A | - | - |
Arnt2 | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Aromatase | + | - | - | - | weak | - | - | - | - | - | N/A | - | - | - | - | N/A | - | - | - | + |
Avp | - | - | - | - | - | - | - | + | weak | + | + | - | - | |||||||
AVPR1a | + | + | N/A | + | N/A | + | + | + | weak | weak | + | + | + | + | + | + | weak | + | + | + |
AVPR1b | weak | + | + | + | N/A | + | + | + | + | + | + | + | + | + | + | weak | + | + | + | + |
BDNF | + | + | + | + | N/A | + | + | + | + | + | + | weak | N/A | + | + | + | weak | weak | weak | + |
BRS-3 | + | + | + | |||||||||||||||||
Calcium Receptor (CaR) | weak | + | N/A | + | + | + | - | + | strong | + | - | + | - | strong | strong | + | - | - | + | + |
CART | weak | + | + | + | N/A | weak | weak | - | - | - | - | - | - | weak | - | + | + | + | weak | + |
CB1 receptor | - | - | N/A | - | - | - | - | N/A | - | - | N/A | - | N/A | N/A | - | - | N/A | N/A | N/A | + |
cc1αb | + | |||||||||||||||||||
cc1αc | + | + | ||||||||||||||||||
ChAT | N/A | - | N/A | N/A | N/A | N/A | N/A | weak | + | weak | - | - | - | - | + | N/A | - | N/A | - | - |
chemerin | weak | weak | + | ? | N/A | ? | + | + | + | + | - | + | weak | + | - | + | + | + | + | + |
chemerinR | + | + | + | + | N/A | + | + | + | + | weak | weak | + | + | + | + | + | + | + | + | + |
CNTFR | + | + | + | + | N/A | + | + | + | + | weak | weak | weak | weak | - | - | + | + | + | + | + |
CRFR1 | weak | - | + | + | + | weak | weak | N/A | - | + | + | N/A | weak | N/A | + | + | - | weak | weak | + |
CRFR2 | + | - | + | + | + | - | - | N/A | weak | - | + | + | + | - | + | + | - | + | - | + |
CRH/CRF | - | - | - | weak | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | weak |
CRLR | N/A | N/A | N/A | N/A | N/A | N/A | N/A | + | + | - | - | + | - | - | - | + | + | N/A | - | + |
DAT | weak | + | + | + | strong | + | + | + | + | - | - | - | - | - | - | + | + | - | + | + |
Dpp4 | - | - | - | - | N/A | - | - | - | + | - | - | - | - | - | - | weak | - | - | - | - |
Dynorphin | - | - | - | - | - | N/A | - | - | - | - | N/A | - | - | - | - | - | - | - | - | - |
ER α | + | + | + | + | + | + | + | - | + | + | - | + | weak | - | - | + | + | + | weak | + |
ER β | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
FIAF | + | + | + | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Gad 1 (Gad 67) | + | + | + | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | - | + |
Gad 2 (Gad 65) | + | - | + | + | + | + | - | - | - | ? | - | ? | - | - | ? | + | - | + | + | + |
Gal | + | + | - | - | + | + | weak | + | - | - | - | - | - | - | - | + | - | - | - | - |
GALP | - | - | - | - | - | - | N/A | N/A | - | - | - | - | - | - | + | - | + | + | - | + |
GCK | N/A | N/A | N/A | N/A | N/A | N/A | N/A | + | + | + | + | + | + | + | + | N/A | + | N/A | + | + |
GFAP | - | - | - | - | - | - | - | N/A | - | |||||||||||
Ghrelin | + | N/A | N/A | - | + | + | - | + | + | - | - | + | - | - | + | + | + | + | + | + |
Ghrelin variant | - | N/A | N/A | + | + | + | - | - | + | - | + | - | - | - | + | weak | - | + | - | + |
GHRH (southern) | weak | + | - | + | - | weak | weak | weak | + | + | + | |||||||||
GHSR1a | + | + | + | + | weak | + | weak | weak | strong | + | + | - | + | + | weak | strong | weak | + | ||
Glp1R | + | - | strong | + | strong | N/A | weak | - | - | - | N/A | - | - | - | - | + | + | + | - | + |
Glp2R | - | - | strong | - | strong | N/A | - | - | - | - | N/A | - | - | - | - | - | - | - | - | strong |
Glucagon receptor | + | + | ? | + | N/A | - | + | - | - | - | + | - | - | - | - | - | + | - | - | - |
Glucocorticoid receptor (GR) | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
GLUT1 | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
GLUT2 | + | - | - | + | - | + | - | - | - | + | weak | - | - | - | - | - | - | - | - | + |
GLUT3 | + | + | + | + | + | + | weak | weak | + | + | + | + | weak | + | + | + | + | + | + | + |
GLUT4 | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
GLUT5 | strong | |||||||||||||||||||
GMR alpha | weak | - | - | - | N/A | ? | + | ? | + | + | + | + | + | + | + | + | + | + | + | + |
GnIH (Rfrp) | ? | ? | ? | ? | N/A | + | + | - | ? | + | - | - | + | - | weak | + | + | strong | + | + |
GnRH | + | weak | + | + | + | + | + | strong | + | weak | - | + | ||||||||
GnRH Receptor | - | - | - | - | - | - | - | - | - | - | ||||||||||
Gpr 39 | + | + | N/A | N/A | + | N/A | + | N/A | + | N/A | N/A | N/A | N/A | N/A | N/A | + | N/A | N/A | N/A | N/A |
Gpr 120 | - | strong | - | weak | weak | N/A | - | - | - | - | N/A | strong | weak | - | weak | - | - | weak | - | strong |
Grp | - | - | weak | + | + | weak | weak | N/A | weak | - | - | - | + | - | + | + | - | weak | - | strong |
GrpR | + | + | + | + | N/A | weak | weak | weak | weak | weak | weak | + | + | + | + | + | + | + | + | + |
Ht1b (5-Ht1b) | + | + | + | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Htr2a (5-Htr2a) | + | - | + | + | + | + | + | + | weak | + | + | + | weak | + | + | + | + | + | weak | + |
Htr2c | - | - | - | - | - | N/A | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
IGF | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
IGF1R | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
IGFBP-1 | - | - | - | - | N/A | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
IL-1 Beta | - | + | + | weak | ||||||||||||||||
Insulin I | - | - | - | - | - | - | - | N/A | - | - | - | - | - | - | - | - | - | - | - | - |
Insulin II | + | - | - | - | - | - | - | N/A | weak | weak | - | - | - | - | - | - | - | + | - | + |
Insulin Receptor | N/A | + | + | N/A | N/A | N/A | N/A | + | + | + | + | + | + | + | + | + | + | N/A | N/A | + |
Insulin receptor substrate 2 | + | + | N/A | + | + | + | + | + | + | + | + | + | + | - | - | - | - | + | + | + |
Kir6.1 | N/A | - | N/A | N/A | N/A | N/A | N/A | - | - | - | - | - | - | - | - | N/A | - | N/A | - | - |
Kir6.2 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | - | + | + | - | ? | - | + | ? | ? | ? | N/A | + | - |
Kisspeptin | + | + | - | + | + | N/A | weak | - | - | weak | - | - | - | - | - | + | - | weak | - | - |
Kiss Receptor (GPR54) | + | + | + | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Lep Receptor | + | weak | weak | + | - | + | + | + | + | - | + | weak | + | + | - | + | + | - | + | + |
Lipoprotein lipase (LPL) | + | - | weak | |||||||||||||||||
mc3R | + | - | + | |||||||||||||||||
mc4R | N/A | N/A | N/A | N/A | N/A | N/A | + | - | - | - | + | + | - | - | - | - | + | N/A | - | + |
MCH | N/A | + | + | N/A | + | N/A | N/A | + | + | + | + | + | + | + | + | + | + | weak | + | + |
MCHR1 | weak | + | + | + | weak | weak | + | + | + | + | + | + | + | + | + | N/A | + | weak | + | + |
New-1 | - | - | - | - | - | - | - | - | - | |||||||||||
New-2 | - | - | - | - | - | - | - | - | - | |||||||||||
New-4 | + | + | + | + | - | + | + | + | - | |||||||||||
NMS (no.3) | + | |||||||||||||||||||
Nmu | + | weak | + | + | + | - | - | + | + | + | - | weak | - | weak | - | + | weak | - | - | - |
NPB | + | + | + | + | + | N/A | + | + | + | + | + | + | weak | + | + | + | + | + | + | + |
NPW | weak | - | + | + | + | NA | + | + | + | weak | weak | weak | weak | weak | weak | weak | weak | weak | - | weak |
NPY | very weak | - | - | - | - | - | weak | - | - | very weak | weak | - | - | - | - | - | - | - | - | - |
NPY-Y1 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | + | + | N/A | + | + | ||||||||
NPY-Y2 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | + | + | N/A | + | + | ||||||||
NPY-Y4 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | + | + | N/A | + | + | ||||||||
NPY-Y5 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | + | - | N/A | - | + | ||||||||
NSE | + | + | + | + | + | + | + | + | + | |||||||||||
NT | - | - | - | - | - | - | - | + | + | + | - | + | + | + | + | strong | + | - | - | + |
NTR1 | - | N/A | N/A | - | + | - | + | + | weak | - | - | weak | - | - | - | + | weak | weak | - | + |
OprlR | + | + | + | + | N/A | + | + | + | - | + | + | + | + | + | + | + | + | + | + | + |
orexin | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
orexin R1 | + | + | + | + | N/A | + | + | + | + | + | - | + | + | + | + | + | + | + | weak | + |
orexin R2 | ? | ? | + | - | N/A | - | + | - | weak | + | + | - | + | - | + | + | + | + | - | + |
Oxytocin | - | - | - | weak | ||||||||||||||||
pAdcyap1 | - | - | - | - | ? | + | - | - | - | - | - | + | - | - | - | - | - | + | - | + |
POMC | ||||||||||||||||||||
proGlu | - | - | - | weak | - | + | - | - | + | - | - | - | - | - | - | - | - | + | - | weak |
proGlu (2007) | - | - | + | + | - | N/A | - | - | - | - | N/A | - | - | - | - | weak | - | weak | - | strong |
PTH2-R | weak | - | N/A | weak | - | weak | weak | weak | weak | weak | - | weak | weak | weak | weak | N/A | - | - | + | weak |
resistin | + | + | + | + | + | N/A | + | + | + | - | - | ? | N/A | - | + | + | - | + | weak | + |
Secretin | + | + | + | strong | strong | N/A | + | weak? | - | - | - | - | - | - | - | - | weak | - | - | - |
5-HT7 receptor | strong | strong | strong | strong | strong | strong | strong | strong | ||||||||||||
SF-1 | + | + | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Sim1 (S1) | not clear | not clear | - | strong | very weak | - | weak | + | - | strong | strong | - | strong | strong | weak | weak | strong | strong | strong | |
Socs-3 | + | + | + | - | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
somatostatin (som) | + | - | + | + | + | weak | + | N/A | ? | - | - | ? | ? | ? | + | + | ? | + | weak | + |
SSTY | + | + | + | + | + | - | - | + | - | |||||||||||
STAT3 | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | N/A | + | + | + | + |
STAT | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | N/A | + | + | + | + |
STAT5B | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | N/A | + | + | + | + |
Sur1 | N/A | - | N/A | N/A | N/A | N/A | N/A | - | - | weak | - | weak | - | - | - | N/A | - | N/A | - | - |
Sur2 | N/A | - | N/A | N/A | N/A | N/A | N/A | - | - | - | - | - | - | - | - | N/A | - | N/A | - | + |
Syndecan 3 | strong | strong | strong | strong | strong | N/A | strong | strong | strong | strong | strong | strong | strong | strong | strong | strong | strong | strong | strong | strong |
T antigen | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
TAC2 (neurokinin B) | ? | weak | - | - | strong | - | weak | weak | - | - | - | - | weak | weak | - | - | - | ? | - | weak |
TH | + | + | - | + | + | + | + | weak | - | weak | weak | - | - | weak | - | - | - | + | - | + |
Tph | - | - | - | - | + | - | - | strong | weak | |||||||||||
THRalpha | + | + | ||||||||||||||||||
THRbeta | + | + | ||||||||||||||||||
TRH | - | - | - | - | N/A | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Ucn | + | weak | weak | + | - | - | + | + | + | + | + | + | + | + | + | + | + | - | - | + |
Ucp2 | + | + | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
VGF | + | + | + | + | N/A | + | weak | weak | + | + | + | + | + | + | + | weak | weak | + | + | + |
VIP | + | - | + | strong | - | strong | + | N/A | + | weak | weak | N/A | + | N/A | + | strong | weak | strong | + | strong |
VIPR1 | weak | + | + | + | N/A | - | weak | - | - | - | - | - | - | - | ? | + | weak | + | - | + |
VIPR2 | + | + | + | + | N/A | + | + | + | + | + | + | + | weak | + | weak | + | + | + | + | + |
MARKER | N-1 | N-3 | N-4 | N-6 | N-7 | N-8 | N-11 | N-20/1 | N-20/2 | N-25/2 | N-25/3 | N-29/1 | N-29/2 | N-29/3 | N-29/4 | N-36/1 | N-36/2 | N-37 | N-38 | N-39 |
Adiponectin receptor 1 | + | + | + | + | + | N/A | RT- bad | + | + | + | + | + | + | + | + | + | + | + | + | + |
Adiponectin receptor 2 | + | + | + | + | + | N/A | RT- bad | + | + | + | + | + | + | + | + | + | + | + | + | + |
Adiponutrin (cDNA) | - | - | - | weak | + | N/A | weak | + | weak | + | ? | + | weak | weak | + | + | - | - | - | - |
Adiponutrin (one-step) | weak | - | + | + | + | N/A | + | + | weak | + | weak | + | weak | + | + | + | weak | weak | weak | weak |
Agrp | + | + | + | + | + | + | + | + | + | + | + | + | + | + | - | + | + | + | + | + |
AhR | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Angiotensinogen | strong | strong | strong | strong | strong | strong | strong | strong | strong | weak | + | + | weak | weak | weak | strong | strong | strong | weak ? | strong |
Angiotension Receptor 1 | strong | strong | - | weak | strong | N/A | weak | weak | - | + | - | strong | - | - | - | weak | - | - | strong | |
Angiotension Receptor 2 | weak | strong | strong | strong | strong | strong | strong | |||||||||||||
AR | - | + | weak | + | - | weak | - | + | + | weak | - | weak | - | weak | - | - | + | N/A | - | - |
Arnt2 | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Aromatase | + | - | - | - | weak | - | - | - | - | - | N/A | - | - | - | - | N/A | - | - | - | + |
Avp | - | - | - | - | - | - | - | + | weak | + | + | - | - | |||||||
AVPR1a | + | + | N/A | + | N/A | + | + | + | weak | weak | + | + | + | + | + | + | weak | + | + | + |
AVPR1b | weak | + | + | + | N/A | + | + | + | + | + | + | + | + | + | + | weak | + | + | + | + |
BDNF | + | + | + | + | N/A | + | + | + | + | + | + | weak | N/A | + | + | + | weak | weak | weak | + |
BRS-3 | + | + | + | |||||||||||||||||
Calcium Receptor (CaR) | weak | + | N/A | + | + | + | - | + | strong | + | - | + | - | strong | strong | + | - | - | + | + |
CART | weak | + | + | + | N/A | weak | weak | - | - | - | - | - | - | weak | - | + | + | + | weak | + |
CB1 receptor | - | - | N/A | - | - | - | - | N/A | - | - | N/A | - | N/A | N/A | - | - | N/A | N/A | N/A | + |
cc1αb | + | |||||||||||||||||||
cc1αc | + | + | ||||||||||||||||||
ChAT | N/A | - | N/A | N/A | N/A | N/A | N/A | weak | + | weak | - | - | - | - | + | N/A | - | N/A | - | - |
chemerin | weak | weak | + | ? | N/A | ? | + | + | + | + | - | + | weak | + | - | + | + | + | + | + |
chemerinR | + | + | + | + | N/A | + | + | + | + | weak | weak | + | + | + | + | + | + | + | + | + |
CNTFR | + | + | + | + | N/A | + | + | + | + | weak | weak | weak | weak | - | - | + | + | + | + | + |
CRFR1 | weak | - | + | + | + | weak | weak | N/A | - | + | + | N/A | weak | N/A | + | + | - | weak | weak | + |
CRFR2 | + | - | + | + | + | - | - | N/A | weak | - | + | + | + | - | + | + | - | + | - | + |
CRH/CRF | - | - | - | weak | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | weak |
CRLR | N/A | N/A | N/A | N/A | N/A | N/A | N/A | + | + | - | - | + | - | - | - | + | + | N/A | - | + |
DAT | weak | + | + | + | strong | + | + | + | + | - | - | - | - | - | - | + | + | - | + | + |
Dpp4 | - | - | - | - | N/A | - | - | - | + | - | - | - | - | - | - | weak | - | - | - | - |
Dynorphin | - | - | - | - | - | N/A | - | - | - | - | N/A | - | - | - | - | - | - | - | - | - |
ER α | + | + | + | + | + | + | + | - | + | + | - | + | weak | - | - | + | + | + | weak | + |
ER β | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
FIAF | + | + | + | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Gad 1 (Gad 67) | + | + | + | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | - | + |
Gad 2 (Gad 65) | + | - | + | + | + | + | - | - | - | ? | - | ? | - | - | ? | + | - | + | + | + |
Gal | + | + | - | - | + | + | weak | + | - | - | - | - | - | - | - | + | - | - | - | - |
GALP | - | - | - | - | - | - | N/A | N/A | - | - | - | - | - | - | + | - | + | + | - | + |
GCK | N/A | N/A | N/A | N/A | N/A | N/A | N/A | + | + | + | + | + | + | + | + | N/A | + | N/A | + | + |
GFAP | - | - | - | - | - | - | - | N/A | - | |||||||||||
Ghrelin | + | N/A | N/A | - | + | + | - | + | + | - | - | + | - | - | + | + | + | + | + | + |
Ghrelin variant | - | N/A | N/A | + | + | + | - | - | + | - | + | - | - | - | + | weak | - | + | - | + |
GHRH (southern) | weak | + | - | + | - | weak | weak | weak | + | + | + | |||||||||
GHSR1a | + | + | + | + | weak | + | weak | weak | strong | + | + | - | + | + | weak | strong | weak | + | ||
Glp1R | + | - | strong | + | strong | N/A | weak | - | - | - | N/A | - | - | - | - | + | + | + | - | + |
Glp2R | - | - | strong | - | strong | N/A | - | - | - | - | N/A | - | - | - | - | - | - | - | - | strong |
Glucagon receptor | + | + | ? | + | N/A | - | + | - | - | - | + | - | - | - | - | - | + | - | - | - |
Glucocorticoid receptor (GR) | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
GLUT1 | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
GLUT2 | + | - | - | + | - | + | - | - | - | + | weak | - | - | - | - | - | - | - | - | + |
GLUT3 | + | + | + | + | + | + | weak | weak | + | + | + | + | weak | + | + | + | + | + | + | + |
GLUT4 | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
GLUT5 | strong | |||||||||||||||||||
GMR alpha | weak | - | - | - | N/A | ? | + | ? | + | + | + | + | + | + | + | + | + | + | + | + |
GnIH (Rfrp) | ? | ? | ? | ? | N/A | + | + | - | ? | + | - | - | + | - | weak | + | + | strong | + | + |
GnRH | + | weak | + | + | + | + | + | strong | + | weak | - | + | ||||||||
GnRH Receptor | - | - | - | - | - | - | - | - | - | - | ||||||||||
Gpr 39 | + | + | N/A | N/A | + | N/A | + | N/A | + | N/A | N/A | N/A | N/A | N/A | N/A | + | N/A | N/A | N/A | N/A |
Gpr 120 | - | strong | - | weak | weak | N/A | - | - | - | - | N/A | strong | weak | - | weak | - | - | weak | - | strong |
Grp | - | - | weak | + | + | weak | weak | N/A | weak | - | - | - | + | - | + | + | - | weak | - | strong |
GrpR | + | + | + | + | N/A | weak | weak | weak | weak | weak | weak | + | + | + | + | + | + | + | + | + |
Ht1b (5-Ht1b) | + | + | + | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Htr2a (5-Htr2a) | + | - | + | + | + | + | + | + | weak | + | + | + | weak | + | + | + | + | + | weak | + |
Htr2c | - | - | - | - | - | N/A | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
IGF | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
IGF1R | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
IGFBP-1 | - | - | - | - | N/A | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
IL-1 Beta | - | + | + | weak | ||||||||||||||||
Insulin I | - | - | - | - | - | - | - | N/A | - | - | - | - | - | - | - | - | - | - | - | - |
Insulin II | + | - | - | - | - | - | - | N/A | weak | weak | - | - | - | - | - | - | - | + | - | + |
Insulin Receptor | N/A | + | + | N/A | N/A | N/A | N/A | + | + | + | + | + | + | + | + | + | + | N/A | N/A | + |
Insulin receptor substrate 2 | + | + | N/A | + | + | + | + | + | + | + | + | + | + | - | - | - | - | + | + | + |
Kir6.1 | N/A | - | N/A | N/A | N/A | N/A | N/A | - | - | - | - | - | - | - | - | N/A | - | N/A | - | - |
Kir6.2 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | - | + | + | - | ? | - | + | ? | ? | ? | N/A | + | - |
Kisspeptin | + | + | - | + | + | N/A | weak | - | - | weak | - | - | - | - | - | + | - | weak | - | - |
Kiss Receptor (GPR54) | + | + | + | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Lep Receptor | + | weak | weak | + | - | + | + | + | + | - | + | weak | + | + | - | + | + | - | + | + |
Lipoprotein lipase (LPL) | + | - | weak | |||||||||||||||||
mc3R | + | - | + | |||||||||||||||||
mc4R | N/A | N/A | N/A | N/A | N/A | N/A | + | - | - | - | + | + | - | - | - | - | + | N/A | - | + |
MCH | N/A | + | + | N/A | + | N/A | N/A | + | + | + | + | + | + | + | + | + | + | weak | + | + |
MCHR1 | weak | + | + | + | weak | weak | + | + | + | + | + | + | + | + | + | N/A | + | weak | + | + |
New-1 | - | - | - | - | - | - | - | - | - | |||||||||||
New-2 | - | - | - | - | - | - | - | - | - | |||||||||||
New-4 | + | + | + | + | - | + | + | + | - | |||||||||||
NMS (no.3) | + | |||||||||||||||||||
Nmu | + | weak | + | + | + | - | - | + | + | + | - | weak | - | weak | - | + | weak | - | - | - |
NPB | + | + | + | + | + | N/A | + | + | + | + | + | + | weak | + | + | + | + | + | + | + |
NPW | weak | - | + | + | + | NA | + | + | + | weak | weak | weak | weak | weak | weak | weak | weak | weak | - | weak |
NPY | very weak | - | - | - | - | - | weak | - | - | very weak | weak | - | - | - | - | - | - | - | - | - |
NPY-Y1 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | + | + | N/A | + | + | ||||||||
NPY-Y2 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | + | + | N/A | + | + | ||||||||
NPY-Y4 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | + | + | N/A | + | + | ||||||||
NPY-Y5 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | + | - | N/A | - | + | ||||||||
NSE | + | + | + | + | + | + | + | + | + | |||||||||||
NT | - | - | - | - | - | - | - | + | + | + | - | + | + | + | + | strong | + | - | - | + |
NTR1 | - | N/A | N/A | - | + | - | + | + | weak | - | - | weak | - | - | - | + | weak | weak | - | + |
OprlR | + | + | + | + | N/A | + | + | + | - | + | + | + | + | + | + | + | + | + | + | + |
orexin | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
orexin R1 | + | + | + | + | N/A | + | + | + | + | + | - | + | + | + | + | + | + | + | weak | + |
orexin R2 | ? | ? | + | - | N/A | - | + | - | weak | + | + | - | + | - | + | + | + | + | - | + |
Oxytocin | - | - | - | weak | ||||||||||||||||
pAdcyap1 | - | - | - | - | ? | + | - | - | - | - | - | + | - | - | - | - | - | + | - | + |
POMC | ||||||||||||||||||||
proGlu | - | - | - | weak | - | + | - | - | + | - | - | - | - | - | - | - | - | + | - | weak |
proGlu (2007) | - | - | + | + | - | N/A | - | - | - | - | N/A | - | - | - | - | weak | - | weak | - | strong |
PTH2-R | weak | - | N/A | weak | - | weak | weak | weak | weak | weak | - | weak | weak | weak | weak | N/A | - | - | + | weak |
resistin | + | + | + | + | + | N/A | + | + | + | - | - | ? | N/A | - | + | + | - | + | weak | + |
Secretin | + | + | + | strong | strong | N/A | + | weak? | - | - | - | - | - | - | - | - | weak | - | - | - |
5-HT7 receptor | strong | strong | strong | strong | strong | strong | strong | strong | ||||||||||||
SF-1 | + | + | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Sim1 (S1) | not clear | not clear | - | strong | very weak | - | weak | + | - | strong | strong | - | strong | strong | weak | weak | strong | strong | strong | |
Socs-3 | + | + | + | - | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
somatostatin (som) | + | - | + | + | + | weak | + | N/A | ? | - | - | ? | ? | ? | + | + | ? | + | weak | + |
SSTY | + | + | + | + | + | - | - | + | - | |||||||||||
STAT3 | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | N/A | + | + | + | + |
STAT | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | N/A | + | + | + | + |
STAT5B | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | N/A | + | + | + | + |
Sur1 | N/A | - | N/A | N/A | N/A | N/A | N/A | - | - | weak | - | weak | - | - | - | N/A | - | N/A | - | - |
Sur2 | N/A | - | N/A | N/A | N/A | N/A | N/A | - | - | - | - | - | - | - | - | N/A | - | N/A | - | + |
Syndecan 3 | strong | strong | strong | strong | strong | N/A | strong | strong | strong | strong | strong | strong | strong | strong | strong | strong | strong | strong | strong | strong |
T antigen | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
TAC2 (neurokinin B) | ? | weak | - | - | strong | - | weak | weak | - | - | - | - | weak | weak | - | - | - | ? | - | weak |
TH | + | + | - | + | + | + | + | weak | - | weak | weak | - | - | weak | - | - | - | + | - | + |
Tph | - | - | - | - | + | - | - | strong | weak | |||||||||||
THRalpha | + | + | ||||||||||||||||||
THRbeta | + | + | ||||||||||||||||||
TRH | - | - | - | - | N/A | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Ucn | + | weak | weak | + | - | - | + | + | + | + | + | + | + | + | + | + | + | - | - | + |
Ucp2 | + | + | + | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
VGF | + | + | + | + | N/A | + | weak | weak | + | + | + | + | + | + | + | weak | weak | + | + | + |
VIP | + | - | + | strong | - | strong | + | N/A | + | weak | weak | N/A | + | N/A | + | strong | weak | strong | + | strong |
VIPR1 | weak | + | + | + | N/A | - | weak | - | - | - | - | - | - | - | ? | + | weak | + | - | + |
VIPR2 | + | + | + | + | N/A | + | + | + | + | + | + | + | weak | + | weak | + | + | + | + | + |
MARKER | N-40 | N-41 | N-42 | N-43 | N-44 | N-45 | N-46 | N-47 | GT1-7 | Hypothalamus | Min6 | MOVAS | GnV3 | GnV4 |
Adiponectin receptor 1 | N/A | + | + | + | + | N/A | + | + | + | + | ||||
Adiponectin receptor 2 | N/A | + | + | + | + | N/A | + | + | + | + | ||||
Adiponutrin (cDNA) | N/A | + | + | + | weak | N/A | weak | weak | + | + | ||||
Adiponutrin (one-step) | N/A | - | + | + | + | weak | + | + | + | + | ||||
Agrp | + | + | + | + | + | + | + | + | + | + | ||||
AhR | + | + | + | 43/5 + | + | + | + | + | weak | + | ||||
Angiotensinogen | weak | strong | weak | weak | weak ? | weak | strong | N/A | + | + | N/A | N/A | ||
Angiotension Receptor 1 | strong | strong | weak | 43/5 - | strong | strong | weak | N/A | strong | N/A | N/A | N/A | - | - |
Angiotension Receptor 2 | weak | - | - | 43/5 - | - | weak | weak | N/A | - | N/A | N/A | N/A | - | - |
AR | + | + | + | + | + | + | + | + | + | + | ||||
Arnt2 | + | + | + | 43/5 + | + | + | + | + | + | + | ||||
Aromatase | + | + | + | 43/5 - | - | - | N/A | + | - | + | N/A | N/A | + | + |
Avp | - | - | 43/5 - | - | - | - | + | + | + | |||||
AVPR1a | + | + | + | 43/5 + | + | + | + | + | weak | + | N/A | N/A | ||
AVPR1b | + | + | + | 43/5 + | + | + | weak | - | + | + | N/A | N/A | ||
BDNF | + | + | N/A | 43/5 + | + | + | + | + | weak | + | N/A | N/A | ||
BRS-3 | - | - | ||||||||||||
Calcium Receptor (CaR) | strong | + | - | 43/5 + | - | + | + | - | strong | strong | ||||
CART | weak | ? | - | 43/5 + | weak | weak | weak | weak | + | + | N/A | N/A | ||
CB1 receptor | N/A | + | + | N/A | + | N/A | + | N/A | weak | + | ||||
cc1αb | + | + | + | |||||||||||
cc1αc | + | + | + | |||||||||||
ChAT | - | - | weak | - | + | - | weak | - | + | + | ||||
chemerin | + | + | + | 43/5 weak | ? | + | + | + | + | + | N/A | N/A | ||
chemerinR | N/A | + | + | 43/5 + | + | N/A | + | + | + | + | N/A | N/A | ||
CNTFR | + | + | + | 43/5 + | + | + | + | + | + | + | N/A | N/A | + | + |
CRFR1 | + | + | + | 43/5 - | strong | N/A | - | N/A | N/A | + | strong | |||
CRFR2 | - | + | + | 43/5 + | - | N/A | + | + | strong | strong | + | |||
CRH(idt) | - | weak | weak | 43/5 weak | weak | - | - | - | - | strong | ||||
CRLR | + | + | + | + | + | + | + | + | - | + | ||||
DAT | + | + | + | + | - | + | + | + | + | + | ||||
Dpp4 | - | - | - | 43/5 - | - | + | + | - | + | + | ||||
Dynorphin | - | - | - | 43/5 - | - | - | - | N/A | N/A | + | ||||
ER α | + | + | + | + | + | + | + | + | + | + | N/A | N/A | N/A | N/A |
ER β | + | + | + | + | + | + | + | + | + | + | ||||
FIAF | N/A | + | + | + | + | + | + | + | + | + | ||||
Gad 1 (Gad 67) | N/A | + | + | + | + | + | + | + | + | + | ||||
Gad 2 (Gad 65) | N/A | + | + | + | + | ? | + | + | + | + | ||||
Gal | + | + | + | + | + | + | + | + | - | + | ||||
GALP | + | + | - | 43/5 - | - | N/A | - | - | N/A | + | N/A | N/A | N/A | N/A |
GCK | N/A | + | + | + | + | + | + | + | + | + | ||||
GFAP | - | + | ||||||||||||
Ghrelin | + | + | + | + | - | - | - | + | + | + | ||||
Ghrelin variant | + | + | - | - | + | - | + | - | + | + | ||||
GHRH (southern) | + | weak | weak | + | + | |||||||||
GHSR1a | + | strong | strong | weak | strong | + | + | n/a | + | |||||
Glp1R | - | + | - | 43/5 - | - | - | - | N/A | strong | strong | N/A | N/A | - | - |
Glp2R | - | weak | - | 43/5 - | - | - | - | N/A | - | strong | N/A | N/A | - | - |
Glucagon receptor | + | + | + | 43/5 weak | + | weak | + | + | - | weak | N/A | N/A | - | - |
Glucocorticoid receptor (GR) | N/A | + | + | 43/5 + | + | N/A | + | + | + | + | ||||
GLUT1 | + | + | + | + | + | + | + | + | + | + | ||||
GLUT2 | + | - | + | 43/5 - | - | + | - | + | strong | + | ||||
GLUT3 | + | + | + | + | + | + | + | + | + | + | ||||
GLUT4 | + | + | + | + | + | + | + | + | + | + | ||||
GMR alpha | + | + | + | 43/5 + | + | + | + | + | weak | + | N/A | N/A | - | - |
GnIH (Rfrp) | + | strong | + | 43/5 + | - | strong | + | + | strong | strong | N/A | N/A | ||
GnRH | + | very weak | strong | - | + | weak | + | N/A | ||||||
GnRH Receptor | - | - | + | |||||||||||
Gpr 39 | ? | + | + | 43/5 + | + | + | N/A | N/A | - | very weak? | N/A | N/A | - | - |
Gpr 120 | weak | weak | - | 43/5 - | - | - | - | N/A | - | strong | N/A | N/A | - | - |
Grp | - | + | - | 43/5 - | weak | N/A | - | weak | strong | strong | - | |||
GrpR | + | + | + | 43/5 + | + | + | + | + | + | + | N/A | N/A | ||
Ht1b (5-Ht1b) | + | + | + | 43/5 + | + | + | + | N/A | + | + | N/A | N/A | - | - |
Htr2a (5-Htr2a) | N/A | + | + | 43/5 + | + | N/A | + | + | - | + | ||||
Htr2c | - | - | - | 43/5 - | - | - | - | N/A | strong | strong | N/A | N/A | - | - |
IGF | + | + | + | 43/5 + | + | + | + | + | + | + | N/A | N/A | N/A | N/A |
IGF1R | + | + | + | 43/5 + | + | + | + | + | + | + | N/A | N/A | N/A | N/A |
IGFBP-1 | - | - | - | 43/5 - | - | - | - | - | - | weak | N/A | N/A | - | - |
IL-1 Beta | - | |||||||||||||
Insulin I | - | - | - | 43/5 - | - | N/A | - | - | N/A | ? | strong | |||
Insulin II | - | - | - | 43/5 - | - | N/A | + | - | N/A | + | strong | |||
Insulin Receptor | + | + | + | + | + | + | + | + | + | + | ||||
Insulin receptor substrate 2 | + | + | + | + | + | + | + | + | + | + | ||||
Kir6.1 | - | - | - | - | - | - | - | - | - | + | ||||
Kir6.2 | N/A | + | + | ? | + | - | - | - | + | + | ||||
Kiss | - | - | - | + | - | - | - | - | - | + | ||||
Kiss Receptor | N/A | + | + | + | + | + | + | + | + | + | ||||
Lep Receptor | weak | + | + | - | + | weak | + | + | + | + | ||||
Lipoprotein lipase (LPL) | strong | + | + | |||||||||||
mc3R | - | - | + | |||||||||||
mc4R | + | - | + | + | ? | + | + | + | + | + | ||||
MCH | + | + | + | + | + | + | + | + | + | + | ||||
MCHR1 | + | + | + | + | + | + | + | + | + | + | ||||
New-1 | - | + | ||||||||||||
New-2 | weak | + | ||||||||||||
New-4 | + | + | ||||||||||||
NMS (no.3) | strong | + | ||||||||||||
Nmu | N/A | + | + | + | + | + | + | + | - | + | ||||
NPB | + | + | weak | 43/5 + | + | + | + | N/A | + | + | N/A | N/A | + | + |
NPW | + | + | + | 43/5 + | + | weak | weak | N/A | - | + | N/A | N/A | - | - |
NPY | - | + | - | - | - | - | weak/+ | - | - | + | ||||
NPY-Y1 | N/A | N/A | + | N/A | N/A | N/A | N/A | N/A | - | + | ||||
NPY-Y2 | N/A | N/A | + | N/A | N/A | N/A | N/A | N/A | + | + | ||||
NPY-Y4 | N/A | N/A | + | N/A | N/A | N/A | N/A | N/A | + | + | ||||
NPY-Y5 | N/A | N/A | + | N/A | N/A | N/A | N/A | N/A | - | + | ||||
NSE | + | N/A | ||||||||||||
NT | + | + | + | + | + | + | + | + | + | + | ||||
NTR1 | - | - | - | weak | - | - | - | - | - | + | ||||
OprlR | + | + | + | 43/5 + | weak | + | + | + | + | + | N/A | N/A | - | - |
orexin | - | - | - | - | - | - | - | - | - | + | ||||
orexin R1 | + | + | weak | 43/5 + | + | + | + | + | weak | + | N/A | N/A | ? | - |
orexin R2 | + | + | + | 43/5 - | - | + | + | + | + | + | N/A | N/A | + | + |
Oxytocin | + | + | ||||||||||||
pAdcyap1 | + | - | - | 43/5 weak | - | - | - | weak | - | + | N/A | |||
POMC | N/A | N/A | + | |||||||||||
proGlu | + | + | - | - | - | - | - | - | + | + | ||||
proGlu (2007) | - | - | weak | 43/5 weak | - | - | - | N/A | + | + | strong | N/A | - | - |
PTH2-R | weak | + | weak | weak | weak | - | - | - | - | + | ||||
resistin | N/A | + | + | + | weak | - | weak | + | + | + | ||||
Secretin | - | strong | + | 43/5 weak | weak | - | - | N/A | - | + | N/A | N/A | - | - |
5-HT7 receptor | strong | |||||||||||||
SF-1 | + | + | + | 43/5 + | + | + | + | + | + | + | ||||
Sim1 (S1) | + | - | + | 43/5 strong | + | + | weak | + | strong | strong | ||||
Socs-3 | + | + | + | + | + | + | + | + | + | + | ||||
somatostatin (som) | ? | weak | + | ? | ? | N/A | + | weak | ? | strong | strong | |||
SSTY | + | + | 43/5 - | + | - | + | - | + | ||||||
STAT3 | + | + | + | + | + | + | + | + | + | + | ||||
STAT | + | + | + | + | + | + | + | + | weak | + | ||||
STAT5B | + | + | + | + | + | + | + | + | + | + | ||||
Sur1 | + | + | + | - | + | - | - | + | + | + | ||||
Sur2 | + | + | + | + | weak | weak | weak | - | - | + | ||||
Syndecan 3 | strong | strong | strong | 43/5 strong | strong | strong | strong | N/A | + | strong | N/A | N/A | + | + |
T antigen | + | + | + | + | + | + | + | + | + | N/A | ||||
TAC2 (neurokinin B) | - | weak | weak | 43/5 - | - | + | strong | weak | + | strong | + | N/A | N/A | N/A |
TH | - | + | + | 43/5 + | - | + | - | + | + | + | ||||
Tph | N/A | + | ||||||||||||
THRalpha | + | |||||||||||||
THRbeta | + | |||||||||||||
TRH | - | - | - | 43/5 - | - | - | - | - | + | + | ||||
Ucn | + | + | + | + | weak | weak | + | + | + | weak | ||||
Ucp2 | + | + | + | 43/5 + | + | + | + | + | + | + | N/A | N/A | + | + |
VGF | + | + | + | 43/5 + | + | + | + | + | + | + | N/A | N/A | ||
VIP | + | strong | + | 43/5 weak | - | N/A | + | N/A | + | strong | weak | |||
VIPR1 | - | + | + | 43/5 + | + | - | + | weak | - | + | N/A | N/A | ||
VIPR2 | + | + | + | 43/5 + | + | + | + | weak | + | + | N/A | N/A |
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