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姜黃素號：458-37-7   
英文名稱：Curcumin；1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione；C.I. 75300；C.I. Natural Yellow 3；Diferuloylmethane   
其他名稱：克扣明；1,7-雙(4-羥基-3-甲氧基苯基)-1,6-庚二烯-3,5-二酮；天然黃3；二阿魏酸甲烷；（E,E）-1，7-雙（4-羥基-3-甲氧基苯基）-1，6-庚二烯-3，5-二酮姜黃素；姜黃色素；川芎內(nèi)酯B   
號：458-37-7   
C21H20O6=368.38   
級別：AR   
含量：≥95.0%   
熔點：182～185℃（2℃間距）   
靈敏度試驗：合格   
乙醇溶解試驗：合格   
灼燒殘渣(以硫酸鹽計)：≤0.4%   
性狀(以下信息僅供參考)：橙黃色結(jié)晶性粉末。溶于冰乙酸和乙醇，遇堿呈紅棕色，遇酸呈淺黃色，不溶于水和乙迷。熔點183℃。有刺激性   
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)制造姜黃試紙，pH 8～9。測定硼   
保存：RT  客戶根據(jù)姜黃素號：458-37-7性質(zhì)、化學(xué)式、分子式、結(jié)構(gòu)式、比重、密度、號、沸點、熔點、水溶性、MSDS、用途、作用、規(guī)格包裝、性狀、注意事項、英文名、別稱、純度、級別等情況，本產(chǎn)品化學(xué)性質(zhì)穩(wěn)定，運輸條件不苛刻，一般儲存在陰涼，干燥，通風良好的地方，遠離不相容的物質(zhì)。保持容器密閉。
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公司提供的姜黃素號：458-37-7*，貨源充足。嚴格的生產(chǎn)質(zhì)量控制體系，包括：優(yōu)級純，分析純，化學(xué)純，試劑級，基準試劑，實驗純，教學(xué)試劑，高純試劑，色譜純，光譜純，電子純。各種包裝規(guī)格，并可提供包裝定制，咨詢訂購。

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The noradrenaline transport via noradrenaline transporters is an active, Na+/Cl- dependent transport process mediated by noradrenaline transporters. Noradrenaline transporters constitute the primary mechanism for inactivation of synaptically released noradrenaline, are targets for multiple antidepressants and psychostimulants, and are deficient in affective and autonomic disorders. In rat brain, noradrenaline transporter is expressed in noradrenergic neuronal somata, axons and dendrites, and hippocampus and cortex, but is absent from epinephrine- and dopamine-containing neurons. At least 13 genetic variations have been reported in the noradrenaline transporter protein that affect noradrenaline re-uptake and concentrations in cerebrospinal fluid in humans. The association between these genetic variations in noradrenaline transporters and several psychiatric and cardiovascular disorders is just emerging. Recently, a single amino acid mutation (hNET-A457P) showed deficiency in noradrenaline transport in an orthostatic intolerance patient. Noradrenaline transporter protein consists of 617 amino acids and has 12 trans-membrane domains, a characteristic feature of many membrane associated solute transporters.
Function : Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
Subunit : Interacts with RHOA in its GTP- and GDP-bound states, and with CDC42 in its GTP-bound state. Interacts with the PDZ 1 domain of BAIAP1.
Subcellular Location : Cytoplasm. Nucleus.
Tissue Specificity : Widely expressed.
Similarity : Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain.
Database links : Swiss-Prot: Q7Z628.1
英文名稱  Anti-NOX5
中文名稱  還原型輔酶Ⅱ氧化酶5/*腺嘌呤二核苷酸磷酸抗體
別    名  NADPH oxidase 5; NADPH oxidase EFhand calcium binding domain 5; NOX5; NOX5_HUMAN; MGC149776; MGC149777.
姜黃素號：458-37-7濃    度  1mg/1ml
規(guī) 格  0.2ml/200μg
抗體來源  Rabbit 
克隆類型  polyclonal
交叉反應(yīng)  Human
產(chǎn)品類型  一抗   
研究領(lǐng)域  細胞生物 信號轉(zhuǎn)導(dǎo) 細胞凋亡 細胞周期蛋白 
蛋白分子量  predicted molecular weight: 84kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from human NOX5
亞    型  IgG
純化方法  affinity purified by Protein A
儲 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500
（石蠟切片需做抗原修復(fù)）
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user. 
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis.
Function : Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis. Isoform v2 and isoform v5 are involved in endothelial generation of reactive oxygen species (ROS), proliferation and angiogenesis and contribute to endothelial response to thrombin.
Subcellular Location : Membrane; Multi-pass membrane protein (Potential). Isoform v2: Endoplasmic reticulum. Isoform v5: Endoplasmic reticulum.
Tissue Specificity : Mainly expressed in pachytene spermatocytes of testis and in lymphocyte-rich areas of spleen and lymph nodes. Isoform v1 is expressed in spleen. Isoform v2 is expressed in testis. Also detected in ovary, placenta, pancreas, cardiac fibroblasts. Expressed in B-cells and prostate malignant cells. Isoform v1 and isoform v3 are expressed in epithelial colorectal adenocarcinoma cells. Isoform v2 and isoform v4 are expressed in endothelial cells. Isoform v1, isoform v2, isoform v3 and isoform v4 are expressed in pulmonary artery smooth muscle cells. Isoform v2 and isoform v5 are