二乙酸螢光素號：596-09-8   
英文名稱：FDA；Fluorescein diacetate；3-Oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl diacetate；Diacetylfluorescein    
其他名稱：二乙酸熒光素；熒光素二乙酸鹽；熒光素二乙酸酯；二乙酰熒光素；熒光素雙醋酸酯；醋酸熒光素；熒光胺雙乙酸鹽；3,6-二乙酸基熒光素   
號：596-09-8    
C24H16O7=416.38    
級別：試劑級   
含量：≥97%   
紅外光譜：Consistent with structure   
性狀(以下信息僅供參考)：白色或淺黃色結(jié)晶粉末。熔點200～203℃，Z大吸收波長 498nm    
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)酯酶底物，用于組織化學(xué)檢驗。熒光基質(zhì)。活細胞染色，用作細胞內(nèi)相互作用及其(細胞)膜滲透性的研究。FDA可透過細胞膜并作為熒光素積蓄在活細胞內(nèi)。由于熒光素較BCECF或Calcein的親水性低，因此熒光素從細胞中滲漏的量也高。FDA也可用于流式細胞儀。熒光素的激發(fā)和發(fā)射波長分別為488 nm和530 nm。   
保存：-20℃，避光二乙酸螢光素號：596-09-8儲存條件：
避光、干燥陰涼處封閉貯存,嚴禁與有毒、有害物品混放、混運。本品為非危險 產(chǎn)品可按一般化學(xué)品運輸,輕搬動輕放,防止日曬、雨淋！受熱、受潮、受光后易喪失活力,保存期短,因此貯存和運輸條件比較苛刻。
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存儲：應(yīng)貯存在干燥清潔避光的環(huán)境中，嚴禁與有毒物質(zhì)混放，以免污染（保質(zhì)期為兩年）。
二乙酸螢光素號：596-09-8主要優(yōu)級純、分級純和化學(xué)純3種：
（1）優(yōu)級純（GR：Guaranteed reagent），又稱一級品或保證試劑，99.8%，這種試劑純度Z高，雜質(zhì)含量Z低，適合于重要精密的分析工作和科學(xué)研究工作，使用綠色瓶簽。
（2）分析純（AR），又稱二級試劑，純度很高，99.7%，略次于優(yōu)級純，適合于重要分析及一般研究工作，使用紅色瓶簽。
（3）化學(xué)純（CP），又稱三級試劑，≥ 99.5%，純度與分析純相差較大，適用于工礦、學(xué)校一般分析工作。使用藍色（深藍色）標簽。
（4）實驗試劑（LR：Laboratory reagent），又稱四級試劑。
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stimulates alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades.
Function : Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades.
Subunit : Interacts with the first PDZ domain of MPDZ. Interacts with PRKCA. Binds TNC, laminin-1, COL5A1 and COL6A2. Interacts with PLG and angiostatin. Binds FGF2 and PDGFA. Interacts with GRIP1, GRIP2 and GRIA2. Forms a ternary complex with GRIP1 and GRIA2 (By similarity). Interacts with LGALS3 and the integrin composed of ITGB1 and ITGA3. Interacts with ITGA4 through its chondroitin sulfate glycosaminoglycan. Interacts with BCAR1, CDC42 and ACK1. Interacts with MMP16.
Subcellular Location : Apical cell membrane. Cell projection > lamellipodium membrane. Localized at the apical plasma membrane it relocalizes to the lamellipodia of astrocytoma upon phosphorylation by PRKCA. Localizes to the retraction fibers. Localizes to the plasma membrane of oligodendrocytes.
Tissue Specificity : Detected only in malignant melanoma cells.
Post-translational modifications : O-glycosylated; contains glycosaminoglycan chondroitin sulfate which are required for proper localization and function in stress fiber formation (By similarity). Involved in interaction with MMP16 and ITGA4.
Phosphorylation by PRKCA regulates its subcellular location and function in cell motility (By similarity).
Similarity : Contains 15 CSPG (NG2) repeats.
二乙酸螢光素號：596-09-8Contains 2 laminin G-like domains.
Database links : UniProtKB/Swiss-Prot: Q6UVK1.2
英文名稱  Anti-NLG1/KIRREL2
中文名稱  樣蛋白2抗體
別    名  FILTRIN; Kin of IRRE-like protein 2; Kin of irregular chiasm-like protein 2; NEPH3; nephrin-like gene 1; Nephrin-like protein 3; NLG1.
濃    度  1mg/1ml
規(guī) 格  0.1ml/100μg  0.2ml/200μg
抗體來源  Rabbit 
克隆類型  polyclonal
交叉反應(yīng)  Human, Mouse, Rat
產(chǎn)品類型  一抗   
研究領(lǐng)域  細胞生物 糖尿病 
蛋白分子量  predicted molecular weight: 75kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from human NLG1/KIRREL2
亞    型  IgG
純化方法  affinity purified by Protein A
儲 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500
（石蠟切片需做抗原修復(fù)）
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user. 
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 KIRREL2 is an immunoglobulin super family gene, it has been found to be expressed in beta cells of pancreatic islets.