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丫啶橙號：10127-02-3   
英文名稱：Acridine orange；Basic orange 3RN；Rhoduline orange；Euchrysine 3RXA；C.I.46005     
其他名稱：吖啶橙；堿性橙14；3,6-雙(二甲基氨基)吖啶化鋅鹽酸鹽   
號：10127-02-3   
C17H20ClN3·0.5ZnCl2·HCl=369.96   
級別：Electrophoresis Grade   
分光有效含量：≥80.0%   
PH(1%)：6.0～7.0   
性狀(以下信息僅供參考)：橙紅色粉末。溶于水、乙醇呈橙黃色帶綠色熒光。遇濃硫酸呈無色帶綠色熒光，稀釋后為橙黃色。水溶液加氫氧化鈉產(chǎn)生黃色沉淀。1%溶液，pH為6.5 ，PH值為8.4～10.4則無熒光。能鑲嵌于兩個相鄰的堿基對之間，使部分雙螺旋DNA松開，該兩個堿基對的距離拉大一倍。這樣的DNA復制過程中，會使DNA鏈增加或缺失一個堿基，造成移碼突變   
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)腫瘤細胞和細菌、核酸染色劑及移碼突變的誘變劑。熒光指示劑。吖啶橙是一種熒光色素，吖啶橙激發(fā)濾光片波長488nm。阻斷濾光片波長515nm。吖啶橙與細胞中DNA和RNA結合量存在差別，可發(fā)出不同顏色的熒光（即著色特異性）   
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保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Nogo is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth, induces collapse of growth cones of chick dorsal root ganglion cells, and inhibits the spreading of 3T3 fibroblasts. Nogo is expressed by oligodendrocytes but not by Schwann cells and associates primarily with the endoplasmic reticulum. Nogo exists in three different splice forms, Nogo-A, -B and -C. NgBR (Nogo-B receptor), also known as nuclear undecaprenyl pyrophosphate synthase 1 homolog, is a 293 amino acid single-pass type I membrane protein that acts as a specific receptor for the amino-terminus of Nogo-B. Through this interaction, NgBR is involved in the regulation of vascular remodeling and angiogenesis. NgBR also enhances Niemann-Pick type C2 protein (NPC2) stabilization. Knockdown of NgBR mRNA leads to decreased NPC2 levels, which results in the hallmarks of NPC2 mutation: increased intracellular cholesterol accumulation and a loss of sterol sensing.
Function : Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator. Able to regulate vascular remodeling and angiogenesis. Its similarity with UPP synthetase proteins suggests that it may act as a scaffold for the binding of isoprenyl lipids and/or prenylated proteins.
丫啶橙號：10127-02-3Subunit : Interacts with DHDDS, promoting its isoprenyltransferase activity. Interacts with NPC2.
Subcellular Location : Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Colocalizes with Nogo-B during VEGF and wound healing angiogenesis.
Similarity : Belongs to the UPP synthase family.
Database links : UniProtKB/Swiss-Prot: Q96E22.1
英文名稱  Anti-NENF/Neudesin
中文名稱  神經(jīng)源性神經(jīng)營養(yǎng)因子抗體
別    名  Cell growth inhibiting protein 47; Cell immortalization-related protein 2; CIR2; Nenf; NENF_HUMAN; Neudesin; Neuron derived neurotrophic factor; Neuron-derived neurotrophic factor; SCIRP10; SCIRP10 related protein; Secreted protein of unknown function; Spinal cord injury related protein 10; SPUF; SPUF protein.
濃    度  1mg/1ml
規(guī) 格  0.2ml/200μg
抗體來源  Rabbit 
克隆類型  polyclonal
交叉反應  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep
產(chǎn)品類型  一抗   
研究領域  細胞生物 神經(jīng)生物學 生長因子和激素 
蛋白分子量  predicted molecular weight: 16kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from human Neudesin
亞    型  IgG
純化方法  affinity purified by Protein A
儲 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500
（石蠟切片需做抗原修復）
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user. 
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.