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俾氏麥棕Y號:10114-58-6
英文名稱:Bismarck brown Y;Vesuvine;Phenylene brown;Bismark brown G;C.I. 21000
其他名稱:俾士麥棕Y;俾斯麥棕TDR;俾斯麥棕GG;俾斯麥棕Y;畢士麥棕Y;堿性棕1;4,4'-[1,3-苯基雙(偶氮)]雙[1,3-苯二胺]鹽酸鹽;俾麥棕;堿性棕G;鹽基棕;堿性棕Ⅰ
號:10114-58-6
C18H18N8?2HCl=419.31
級別:BS
熔點:≥300℃
λmax :457 nm
性狀(以下信息僅供參考):棕色至黑棕色粉末。易溶于水呈黃光棕色,微溶于乙醇和溶纖素,不溶于丙同、苯、四錄化碳;遇濃硫酸呈棕色,稀釋后為紅光棕色。遇硝酸呈橙色轉(zhuǎn)為黃色,其水溶液加鹽酸不變色,加10%氫氧化鈉液呈橙色沉淀
用途:本品僅供科研,不得用于其它用途。
保存:RT 俾氏麥棕Y號:10114-58-6儲存條件:
避光、干燥陰涼處封閉貯存,嚴禁與有毒、有害物品混放、混運。本品為非危險 產(chǎn)品可按一般化學品運輸,輕搬動輕放,防止日曬、雨淋!受熱、受潮、受光后易喪失活力,保存期短,因此貯存和運輸條件比較苛刻。
運輸:汽車運輸、EMS郵政快遞,申通快遞等, 款到上海3天內(nèi)發(fā)貨;
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存儲:應(yīng)貯存在干燥清潔避光的環(huán)境中,嚴禁與有毒物質(zhì)混放,以免污染(保質(zhì)期為兩年)。
俾氏麥棕Y號:10114-58-6主要優(yōu)級純、分級純和化學純3種:
(1)優(yōu)級純(GR:Guaranteed reagent),又稱一級品或保證試劑,99.8%,這種試劑純度Z高,雜質(zhì)含量Z低,適合于重要精密的分析工作和科學研究工作,使用綠色瓶簽。
(2)分析純(AR),又稱二級試劑,純度很高,99.7%,略次于優(yōu)級純,適合于重要分析及一般研究工作,使用紅色瓶簽。
(3)化學純(CP),又稱三級試劑,≥ 99.5%,純度與分析純相差較大,適用于工礦、學校一般分析工作。使用藍色(深藍色)標簽。
(4)實驗試劑(LR:Laboratory reagent),又稱四級試劑。
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Gaucher disease, schizophrenia and Usher syndrome, map to chromosome 1.
Function : Displays neurotrophic activity and activates phosphorylation of MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT in primary cultured neurons. Does not have mitogenic activity in primary cultured astrocytes. May play a role on neuronal differentiation and may have a transient effect on neural cell proliferation in neural precursor cells. Neurotrophic activity is enhanced by binding to heme.
Subcellular Location : Secreted > extracellular space.
Similarity : Belongs to the cytochrome b5 family. MAPR subfamily.
Contains 1 cytochrome b5 heme-binding domain.
Database links : UniProtKB/Swiss-Prot: Q9UMX5.1
英文名稱 Anti-Neuronatin
中文名稱 胚胎神經(jīng)細胞NNAT抗體
別 名 Neuronatin; Nnat; NNAT_HUMAN; Peg 5; Peg5.
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, Rabbit
產(chǎn)品類型 一抗
研究領(lǐng)域 腫瘤 細胞生物 發(fā)育生物學 神經(jīng)生物學 細胞分化
蛋白分子量 predicted molecular weight: 9kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Neuronatin
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 The paternally imprinted Neuronatin gene (NNAT) is initially expressed in rhombomeres and the pituitary gland and is later expressed more widely, but much less abundantly, in the central and peripheral nervous systems. The human NNAT gene maps to chromosome 20q11.23 and contains an imprinting region associated with morphological abnormalities and early neonatal lethality. Specifically, hypermethylation of the NNAT gene occurs in both myeloid and lymphoid acute pediatric leukemias and may inhibit NNAT expression. The Neuronatin protein consists of two isoforms, alpha and beta, which are the products of alternative splicing. The alpha form of the Neuronatin gene is encoded by three exons, whereas the beta form is missing the second exon. Neuronatin mRNA expression is abundant in undifferentiated PC-12 cells. Treatment of these cells with nerve growth factor (NGF), which contributes to neuronal differentiation, downregulates Neuronatin mRNA expression. NNAT (-) 1.9 PC-12 cells exhibit an increase in nigericin, rotenone and valinomcin sensitivity; NNAT transfection restores wild-type PC-12 resistance. These results suggests a potential protective role for Neuronatin against toxic insult during development.
Function : May participate in the maintenance of segment identity in the hindbrain and pituitary development, and maturation or maintenance of the overall structure of the nervous system. May function as a regulatory subunit of ion channels.
Similarity : Belongs to the neuronatin family.
英文名稱 Anti-NPY5R
中文名稱 神經(jīng)肽Y受體5抗體
別 名 Neuropeptide Y receptor type 5; Neuropeptide Y receptor Y5; NPY 5R; NPY R5; NPY Y5; NPY Y5 receptor; NPY-Y5 receptor; NPY5 R; NPY5-R; NPY5R; NPY5R_HUMAN; NPYR 5; NPYR5; NPYY 5; NPYY5; NPYY5-R; Y5 receptor.
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
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