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姬姆薩氏色素號(hào):51811-82-6
英文名稱:Giemsa′s Stain;3-(Dimethylamino)-7-aminophenothiazin-5-ium chloride;Azure mixture sicc. Giemsa stain
其他名稱:吉氏色素;姬姆色素;吉氏溶液;吉姆氏色素;姬姆氏色素;吉姆薩染料;姬姆氏色素染料;3-(二甲基氨基)-7-氨基吩噻嗪-5-鎓化物
號(hào):51811-82-6
C14H14ClN3S=291.80
級(jí)別:BS
層析試驗(yàn):合格
干燥失重:≤10.0%
生物染色試驗(yàn):合格
灼燒殘?jiān)?le;2.0%
性狀(以下信息僅供參考):藍(lán)紫色粉末。本品含有一號(hào)天青、二號(hào)天青及二號(hào)天青曙紅等數(shù)種化合物,可用不同量的*及曙紅混合制成。應(yīng)用時(shí)溶于等量甲醇和甘油中。溶液呈藍(lán)色,是中性染料。
用途:本品僅供科研,不得用于其它用途。(以下用途僅供參考)生物染色劑??捎糜谥谱餮和科瑱z查寄生性原生動(dòng)物,如瘧原蟲、錐蟲(trypanosomes);對(duì)致病性螺旋體(如Leptospira,Borrelia等)、病毒、立克次氏體、過氧化酶、染色體等染色;也可應(yīng)用于組織培養(yǎng)研究和試劑。
保存:RT
客戶根據(jù)姬姆薩氏色素號(hào):51811-82-6性質(zhì)、化學(xué)式、分子式、結(jié)構(gòu)式、比重、密度、號(hào)、沸點(diǎn)、熔點(diǎn)、水溶性、MSDS、用途、作用、規(guī)格包裝、性狀、注意事項(xiàng)、英文名、別稱、純度、級(jí)別等情況,本產(chǎn)品化學(xué)性質(zhì)穩(wěn)定,運(yùn)輸條件不苛刻,一般儲(chǔ)存在陰涼,干燥,通風(fēng)良好的地方,遠(yuǎn)離不相容的物質(zhì)。保持容器密閉。
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diagnostic applications.
產(chǎn)品介紹 NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system.
Function : May mediate uptake of degraded synaptic material which could play an important role in synaptic remodeling. Can mediate the neuronal and glial uptake of the snake venom toxin taipoxin.
Subcellular Location : Cytoplasmic vesicle, secretory vesicle (Potential).
Similarity : Contains 1 pentaxin domain.
Database links : UniProtKB/Swiss-Prot: Q15818.2
英文名稱 Anti-Neuroserpin
中文名稱 *或半*蛋白水解酶抑制蛋白1抗體
別 名 Neuroserpin; NEUS_HUMAN; Peptidase inhibitor 12; PI-12; PI12; Protease inhibitor 12; Serine or cysteine proteinase inhibitor clade I (neuroserpin) member 1; Serine or cysteine proteinase inhibitor clade I member 1; Serpin I1; Serpin peptidase inhibitor clade I (neuroserpin) member 1; 姬姆薩氏色素號(hào):51811-82-6克隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep
產(chǎn)品類型 一抗
研究領(lǐng)域 細(xì)胞生物 神經(jīng)生物學(xué)
蛋白分子量 predicted molecular weight: 45kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Neuroserpin
亞 型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Neuroserpin is an axonally secreted glycoprotein in the central nervous system (CNS) that belongs to the family of protease inhibitors known as serpins (1,2). Neuroserpin is a serine-protease inhibitor (3) that forms SDS-stable complexes with tissue plasminogen activator (tPA), urokinase and plasmin, but not thrombin (2,4,5). Neuroserpin is expressed in the neocortex, the hippocampal formation, the olfactory bulb and the amygdala in the adult CNS, and it is expressed in the cerebellum, the granule cells and a subgroup of Purkinje cells in the developing embryo (2). tPA expression has been linked to "neuronal plasticity", either in the developing embryo CNS (2,4) or in cases of synpatic remodeling or long-term potentiation (6). Overexpression of tPA may promote neuronal cell death (6). Mutations in the gene which codes for neuroserpin are linked to hereditary dementia (7). Intracerebral administration of neuroserpin after stroke decreases stroke volume and diminishes the apoptotic features of the resulting ischemic penumbra (6).
Function : Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
Subcellular Location : Secreted.
Tissue Specificity : Predominantly expressed in the brain.
DISEASE : Defects in SERPINI1 are the cause of familial encephalopathy with neuroserpin inclusion bodies (FEN1B) [MIM:604218]. FEN1B is characterized clinically as an autosomal dominantly inherited dementia, histologically by unique neuronal inclusion bodies and biochemically by polymers of neuroserpin.
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