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Anti-Karyopherin beta 3抗體,核轉(zhuǎn)運蛋白β3抗體產(chǎn)品介紹:Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
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保存條件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
連續(xù)使用時4°C存儲,保質(zhì)期六個月,*存儲時建議分裝為10ul以上小包裝-20°C存儲,并避免反復凍融,保質(zhì)期一年。
產(chǎn)品名稱 Anti-Karyopherin beta 3抗體,核轉(zhuǎn)運蛋白β3抗體
產(chǎn)品編號 BYK-17075R
英文名稱 Karyopherin beta 3
中文名稱 核轉(zhuǎn)運蛋白β3抗體
別 名 DKFZp686O1576; FLJ43041; IMB3; Imp5; Importin 5; Importin beta 3 subunit; Importin subunit beta 3; Importin subunit beta-3; Importin-5; IPO 5; IPO5; IPO5_HUMAN; Karyopherin beta 3; Karyopherin beta-3; KPNB3; MGC2068; Pse1; Ran binding protein 5; Ran GTP binding protein 5; Ran-binding protein 5; RanBP 5; RanBP5.
研究領(lǐng)域 細胞生物 染色質(zhì)和核信號 信號轉(zhuǎn)導 結(jié)合蛋白
抗體來源 Rabbit or Mouse
克隆類型 Polyclonal or Monoclonal
交叉反應、產(chǎn)品應用 (具體交叉反應與產(chǎn)品應用請)
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