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當(dāng)前位置:上海博研生物科技有限公司>>科研抗體>>一抗>> 周期素依賴性激酶1抗體,Anti-CDK1/Cdc2抗體

周期素依賴性激酶1抗體,Anti-CDK1/Cdc2抗體

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“周期素依賴性激酶1抗體,Anti-CDK1/Cdc2抗體"應(yīng)用于IHC、WB、 IF、IP、ELISA,質(zhì)量保證,無效免費退換,另外本公司生產(chǎn)經(jīng)營各種標(biāo)記二抗、免疫印跡常用試劑、免疫組化常用試劑,咨詢!

周期素依賴性激酶1抗體,Anti-CDK1/Cdc2抗體”應(yīng)用于IHC、WB、 IF、IP、ELISA,質(zhì)量保證,無效免費退換,另外本公司生產(chǎn)經(jīng)營各種標(biāo)記二抗、免疫印跡常用試劑、免疫組化常用試劑,咨詢!

產(chǎn)品介紹:

【產(chǎn)品名稱】:周期素依賴性激酶1抗體,Anti-CDK1/Cdc2抗體

【產(chǎn)品類型】:一抗


【產(chǎn)品編號】:BYk-0542R                    

【相關(guān)標(biāo)記】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647


【性 狀】: Lyophilized or Liquid


【濃 度】: 1mg/1ml


【亞 型】: IgG


【規(guī) 格】:0.1ml/100ug,0.2ml/200ug


【抗體來源】: Rabbit OR MOUSE


【克隆類型】: polyclonal or monoclonal

【產(chǎn)品用途】:科研實驗,用于免疫組化實驗,WB實驗、IF、IP、ELISA實驗,相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,F(xiàn)ITC標(biāo)記,BIO等。


【貯 存】: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


【詳細(xì)介紹】: The cell division control protein cdc2, also known as cyclin dependent kinase 1 (Cdk1) or p34/cdk1, plays a key role in the control of the eukaryotic cell cycle, where it is required for entry into S phase and mitosis. Cdc2 exists as a complex with both cyclin A and cyclin B. The best characterized of these associations is the Cdc2 p34 cyclin B complex, which is required for the G2 to M phase transition. Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161. However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14. Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase. The isoform CDC2deltaT is found in breast cancer tissues. Furthermore, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration.

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