背景介紹：This gene encodes a calcium transporter that localizes to the mitochondrial inner membrane. The encoded protein interacts with mitochondrial calcium uptake 1. Alternative splicing results in multiple transcript variants.

Function:
Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways. Activity is regulated by MICU1 and MICU2 that stimulate and inhibit MCU activity, respectively. Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake. Involved in buffering the amplitude of systolic calcium rises in cardiomyocytes.

別名：MCU_HUMAN; C10orf42; Ccdc109a; Coiled-coil domain-containing protein 109A; Mitochondrial Calcium Uniporter. 

線粒體鈣離子單向轉(zhuǎn)運蛋白MCU抗體,MCU抗體簡單介紹：

產(chǎn)品編號：BYK-18739R

英文名稱：Anti-MCU
中文名稱：線粒體鈣離子單向轉(zhuǎn)運蛋白MCU抗體

產(chǎn)品規(guī)格：50ul；100ul；200ul；1ml，*

抗體來源 Rabbit or Mouse

克隆類型 Polyclonal or Monoclonal

交叉反應(yīng)、產(chǎn)品應(yīng)用 （具體交叉反應(yīng)與產(chǎn)品應(yīng)用請或添加客服直接索?。?/span>

性    狀 Lyophilized or Liquid
濃    度 1mg/ml

線粒體鈣離子單向轉(zhuǎn)運蛋白MCU抗體,MCU抗體產(chǎn)品信息：

免疫熒光單染（間接法）
1.石蠟切片正常脫蠟至水，PBS洗5分鐘，2次
2.抗原修復(fù)，0.01M枸櫞酸修復(fù)液，沸水浴熱修復(fù)15分鐘
3.正常山羊血清封閉20分鐘，37℃
4.一抗孵育，4℃過夜。
5.PBS洗5分鐘，3次
6.熒光標(biāo)記二抗孵育，37℃，90分鐘
7.PBS洗5分鐘，3次
8.DAPI復(fù)染，PBS洗5分鐘，3次
9.防淬滅熒光封片劑封片
10.鏡檢

線粒體鈣離子單向轉(zhuǎn)運蛋白MCU抗體,MCU抗體相關(guān)產(chǎn)品：

Anti-RELN/Reelin 絡(luò)絲蛋白抗體
Anti-GNAT2 G蛋白轉(zhuǎn)錄因子α2/Gα t2抗體
Anti-Rat secretory IgA  分泌型免疫球蛋白A抗體
Anti-Pan-ras  Pan ras抗體
Anti-ENTPD2/CD39L1 CD39樣蛋白1抗體
Anti-RASSF1A Ras相關(guān)區(qū)域家族1A抗體
Anti-Miz1/ZNF60  鋅指蛋白60抗體
Anti-RAR Beta 維甲酸受體β抗體
Anti-RAR alpha 維甲酸受體RAR α/RAR α抗體
Anti-LC3A/B 自噬微管相關(guān)蛋白輕鏈3A/3B抗體
Anti-phospho-c-Raf(Ser338/Tyr340) 磷酸化原癌基因c-Raf抗體
Anti-RAP1A 抗Rap1A抗體
Anti-ATRNL1 ATRNL1蛋白抗體