背景介紹：MSP58 is a 462 amino acid protein that localizes to the nucleus and contains one FHA domain. Expressed at high levels during the S phase of the cell cycle and present in testis, prostate, thymus, spleen and colon, MSP58 functions to modulate the transcriptional activity of Daxx (a transcriptional repressor) by recruiting Daxx to the nucleolus. Additionally, MSP58 may play a role in the inhibition of TERT omerase activity, further implicating MSP58 as an important protein in transcriptional regulation. The gene encoding MSP58 maps to human chromosome 12 and is expressed as multiple alternatively spliced isoforms. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome and is associated wirh hypochondrogenesis, achondrogenesis and Kniest dysplasia.

別名：58 kDa microspherule protein; Cell cycle regulated factor (78 kDa); Cell cycle regulated factor p78; Cell cycle-regulated factor p78; ICP22BP; INO80 complex subunit J; MCRS 1; MCRS 2; MCRS1; MCRS1_HUMAN; MCRS2; Microspherule protein 1; MSP 58; MSP58; p78. 

細(xì)胞周期調(diào)控因子P78抗體,Anti-MCRS1抗體簡(jiǎn)單介紹：

產(chǎn)品編號(hào)：BYK-18734R

英文名稱(chēng)：Anti-MCRS1
中文名稱(chēng)：細(xì)胞周期調(diào)控因子P78抗體

產(chǎn)品規(guī)格：50ul；100ul；200ul；1ml，*

抗體來(lái)源 Rabbit or Mouse

克隆類(lèi)型 Polyclonal or Monoclonal

交叉反應(yīng)、產(chǎn)品應(yīng)用 （具體交叉反應(yīng)與產(chǎn)品應(yīng)用請(qǐng)或添加客服直接索?。?/span>

性    狀 Lyophilized or Liquid
濃    度 1mg/ml

細(xì)胞周期調(diào)控因子P78抗體,Anti-MCRS1抗體產(chǎn)品信息：

免疫熒光單染（間接法）
1.石蠟切片正常脫蠟至水，PBS洗5分鐘，2次
2.抗原修復(fù)，0.01M枸櫞酸修復(fù)液，沸水浴熱修復(fù)15分鐘
3.正常山羊血清封閉20分鐘，37℃
4.一抗孵育，4℃過(guò)夜。
5.PBS洗5分鐘，3次
6.熒光標(biāo)記二抗孵育，37℃，90分鐘
7.PBS洗5分鐘，3次
8.DAPI復(fù)染，PBS洗5分鐘，3次
9.防淬滅熒光封片劑封片
10.鏡檢

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