背景介紹：This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LAMN1 (lectin mannose binding protein 1; also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D); a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms. 

別名：Melanin concentrating hormone;PMCH; MCH_HUMAN; Pro MCH; Pro melanin concentrating hormone. 

黑色素聚集激素抗體,Anti-PMCH抗體簡(jiǎn)單介紹：

產(chǎn)品編號(hào)：BYK-18725R

英文名稱：Anti-PMCH
中文名稱：黑色素聚集激素抗體

產(chǎn)品規(guī)格：50ul；100ul；200ul；1ml，*

抗體來源 Rabbit or Mouse

克隆類型 Polyclonal or Monoclonal

交叉反應(yīng)、產(chǎn)品應(yīng)用 （具體交叉反應(yīng)與產(chǎn)品應(yīng)用請(qǐng)或添加客服直接索?。?/span>

性    狀 Lyophilized or Liquid
濃    度 1mg/ml

黑色素聚集激素抗體,Anti-PMCH抗體產(chǎn)品信息：

免疫熒光染色與免疫組化前期處理相同，因?yàn)閮?nèi)源性過氧化物酶對(duì)免疫熒光實(shí)驗(yàn)沒有影響，同時(shí)雙氧水反而會(huì)干擾到熒光素發(fā)光，所以這步操作在免疫熒光中不需要做。

常用的熒光顯微鏡一般有三個(gè)通路，激發(fā)波長(zhǎng)為350nm、488nm、555nm附近，分別對(duì)應(yīng)的熒光發(fā)射光顏色為藍(lán)光、綠光、紅光。

350nm常用熒光素：DAPI（復(fù)染用），Alexa Fluor 350

488nm常用熒光素：FITC，Alexa Fluor 488

555nm常用熒光素：PE、Cy3、Rhodamine B、Alexa Fluor555

另有其他常見熒光素

594nm常用熒光素：Texas Red、Alexa Fluor594

647nm常用熒光素：Cy5、APC、Alexa Fluor647

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