背景介紹：This gene encodes a member of the myristoylated alanine-rich C-kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10.

Function:
Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems.

別名：F52; Mac MARCKS; Mac-MARCKS; MacMARCKS; Macrophage enriched Myristoylated Alanine Rich C Kinase Substrate Like Protein; Macrophage myristoylated alanine-rich C kinase substrate; MARCKS like 1; MARCKS like protein 1; MARCKS related protein; MARCKS-like protein 1; MARCKS-related protein; MARCKSL1; MLP; MLP1; MRP; MRP_HUMAN.  

MARCKS樣蛋白1抗體,Anti-MARCKSL1抗體簡單介紹：

產(chǎn)品編號：BYK-18678R

英文名稱：Anti-MARCKSL1
中文名稱：MARCKS樣蛋白1抗體

產(chǎn)品規(guī)格：50ul；100ul；200ul；1ml，*

抗體來源 Rabbit or Mouse

克隆類型 Polyclonal or Monoclonal

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性    狀 Lyophilized or Liquid
濃    度 1mg/ml

MARCKS樣蛋白1抗體,Anti-MARCKSL1抗體產(chǎn)品信息：

各種HRP酶標記成抗體的效價測定程序如下（如：羊抗鼠IgG-HRP的效價測定）：

1、抗原包板：15ug/ml 小鼠IgG-pH9.6·CB液 0.1ml/孔；

2、37°C包被60min或4°C過夜；

3、PBST洗板3次，5min/次；

4、加入倍比稀釋的HRP標記抗體 0.1ml/孔；

5、37°C 30min；

6、PBST洗板5min/次×3；

7、底物液0.1ml/孔 37°C 5-10min；

8、終止液：2N H2SO4 0.05ml/孔；

9、450nm 測定OD值；

陽性OD值比對照值大3倍，為判斷效價稀釋度。

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