Anti-CNG3抗體簡單介紹：

產(chǎn)品編號：BYK-10772R

英文名稱：Anti-CNG3
中文名稱：視錐感光細胞環(huán)磷酸鳥苷門控通道蛋白CNG3抗體

別名：ACHM2; CCNC1; CCNCa; CCNCalpha; CNCG3; CNG 3; CNG-3; CNG channel alpha 3; CNG channel alpha-3; CNG-3; CNG3; CNGA3; Cnga3 cyclic nucleotide gated channel alpha 3; CNGA3_HUMAN; Cone photoreceptor cGMP gated channel; Cone photoreceptor cGMP gated channel alpha subunit; Cone photoreceptor cGMP gated channel subunit alpha; Cone photoreceptor cGMP-gated channel subunit alpha; Cyclic nucleotide gated cation channel alpha 3; Cyclic nucleotide gated channel alpha 3; Cyclic nucleotide gated channel olfactory 3; Cyclic nucleotide gated channel rod photoreceptor subunit alpha; Cyclic nucleotide-gated cation channel alpha-3; Cyclic nucleotide-gated channel alpha-3.  

背景介紹：Cyclic nucleotide-gated (CNG) cation channels are heteromeric complexes made up of principal alpha and modulatory beta subunits. The alpha subunits consist of CNG1-3 and form functional cation channels by themselves. The beta subunits consist of CNG4-6 and, unlike the alpha subunits, do not form functional channels, but rather modify the properties of channels. CNG channels are essential components of olfactory and visual transduction. In olfactory neurons, CNG2, CNG4.3 and CNG5 form Ca2+ permeable channels, which open and depolarize the cell in response to cAMP. In rod photoreceptors, CNG1 and CNG4.1 combine to form Ca ion permeable channels, which give rise to a current in response to cGMP. CNG3 and CNG6 are expressed in cone receptors and may combine to form a native cGMP-activated channel. CNG channels have been implicated in other areas. CNG1 is also expressed in medium-sized and small-sized arteries, suggesting a role for CNG in the regulation of arterial blood pressure and of blood supply to different regions. CNG1, CNG4.1 and CNG4.2 have been detected in the rat pineal gland. CNG2, CNG4.3 and CNG5 are present in GT1 cell lines and may play a role in the secretion of gonadotropin-releasing hormone.

產(chǎn)品規(guī)格：50ul；100ul；200ul；1ml，*

抗體來源 Rabbit or Mouse

克隆類型 Polyclonal or Monoclonal

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性    狀 Lyophilized or Liquid
濃    度 1mg/ml

Anti-CNG3抗體產(chǎn)品信息：

初次體液免疫是指宿主*次接觸外來TD抗原后血清中逐漸出現(xiàn)抗原特異性抗體的過程。初次體液免疫應答的延遲相（從抗原免疫到抗體水平達到高峰的時間）為6-10天，起初幾天血清中的抗原特異性抗體主要為親和力較低的IgM,后期以IgG為主。初次應答過程的血清中抗原特異性抗體的高峰濃度較低且維持時間較短。再次體液免疫應答是指曾被某抗原免疫過的宿主再次接觸該抗原時血清中迅速出現(xiàn)抗原特異性抗體的過程，其延遲相僅為4-5天，血清抗體以IgG為主，其高峰濃度較高且維持時間較長。再次應答所產(chǎn)生的抗體還有親和力成熟現(xiàn)象，即該抗體與抗原的親和力明顯高于初次應答產(chǎn)生的抗體。

免疫應答過程：

1.抗原進入機體；

2.抗原刺激 B淋巴細胞，使之分化增殖成為抗體分泌漿細胞和記憶細胞（初次免疫應答）；

3.抗體主要由漿細胞分泌 ；

4.記憶細胞再次受到特異性抗原刺激后會被激活而成為分泌抗體的漿細胞（再次免疫應答）；

5.記憶B細胞是長命細胞，可以存活數(shù)月甚至機體終生

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