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更新時間:2017-12-04 16:58:10瀏覽次數(shù):121次
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背景介紹:The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.
英文名稱:Anti-ABCD2
中文名稱:三磷酸腺苷結合盒轉運蛋白2抗體
產(chǎn)品規(guī)格:50ul;100ul;200ul;1ml,*
三磷酸腺苷結合盒轉運蛋白2抗體|Anti-ABCD2抗體簡單介紹:
產(chǎn)品編號:BYK-10646R
別名:ABC39; Abcd2; ABCD2_HUMAN; Adrenoleukodystrophy-like 1; Adrenoleukodystrophy-related protein; ALDL1; ALDR; ALDRP; ATP-binding cassette sub-family D member 2; hALDR.
抗體來源 Rabbit or Mouse
克隆類型 Polyclonal or Monoclonal
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性 狀 Lyophilized or Liquid
濃 度 1mg/ml
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