Anti-MTF2抗體，金屬調(diào)節(jié)轉(zhuǎn)錄因子2抗體產(chǎn)品信息：

背景介紹：Binds to the metal-regulating-element (MRE) of metallothionein gene promoter. May be involved in the activation of MT (metallothionein) genes in response to heavy-metal ions.

Function:
Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex, leading to enhance PRC2 H3K27me3 methylation activity. Regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation. Promotes recruitment of the PRC2 complex to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells. Required to repress Hox genes by enhancing H3K27me3 methylation of the PRC2 complex. In some conditions may act as an inhibitor of PRC2 activity: able to activate the CDKN2A gene and promote cellular senescence by suppressing the catalytic activity of the PRC2 complex locally. Binds to the metal-regulating-element (MRE) of MT1A gene promoter (By similarity).

英文名稱：Anti-MTERFD2
中文名稱：金屬調(diào)節(jié)轉(zhuǎn)錄因子2抗體

產(chǎn)品規(guī)格：50ul；100ul；200ul；1ml，*

Anti-MTF2抗體，金屬調(diào)節(jié)轉(zhuǎn)錄因子2抗體簡單介紹：

產(chǎn)品編號：BYK-17872R

別名：DJ976O13.2; hPCl2; M96; metal regulatory transcription factor 2; Metal response element binding transcription factor 2; metal-response element DNA-binding protein M96; PCL2; MTF2_HUMAN; polycomb-like 2; polycomb-like protein 2; Putative DNA binding protein; RP5 976O13.1; RP5-976O13.1; TDRD19A; tudor domain containing 19A. 

抗體來源 Rabbit or Mouse

克隆類型 Polyclonal or Monoclonal

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性    狀 Lyophilized or Liquid
濃    度 1mg/ml

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