Anti-APC10抗體,細胞周期后期促進蛋白亞基10抗體技術說明產(chǎn)品詳細資料
產(chǎn)品編號 BYK-12483R
英文名稱 APC10
中文名稱 細胞周期后期促進蛋白亞基10抗體
別 名 ANAPC 10; anapc10; Anaphase promoting complex 10; Anaphase promoting complex subunit 10; Anaphase-promoting complex subunit 10; Apc 10; APC10; APC10_HUMAN; Cyclosome subunit 10; DKFZP564L0562; Doc 1; Doc1; OTTHUMP00000220297; OTTHUMP00000220298; OTTHUMP00000220299; OTTHUMP00000220300; OTTHUMP00000220303.
研究領域 細胞生物 細胞周期蛋白 泛素
抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產(chǎn)品應用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產(chǎn)品應用不做依據(jù)，具體產(chǎn)品應用與實驗稀釋比請！021-6034 0810
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
亞 型 IgG
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Anti-APC10抗體,細胞周期后期促進蛋白亞基10抗體技術說明產(chǎn)品介紹：
Composed of more than ten subunits, the anaphase-promoting complex (APC) acts in a cell-cycle dependent manner to promote the separation of sister chromatids during the transition between metaphase and anaphase in mitosis. APC, or cyclosome, accomplishes this progression through the ubiquitination of mitotic cyclins and other regulatory proteins that are targeted for destruction during cell division. APC is phosphorylated, and thus activated, by protein kinases Cdk1/cyclin B and polo-like kinase (Plk). APC is under tight control by a number of regulatory factors, including CDC20, CDH1 and MAD2. Specifically, CDC20 and CDH1 directly bind to and activate the cyclin-ubiquitination activity of APCs. In contrast, MAD2 inhibits APC by forming a ternary complex with CDC20 and APC, thus preventing APC activation. APC10 contains a Doc1 homology domain, which is a beta-sandwich structure common to many other putative E3 ubiquitin ligases. APC10 binds to core APC subunits throughout the cell cycle. Specifically, APC10 binds to the C-terminus of CDC27/APC3. During mitosis, APC10 is localized in centrosomes and mitotic spindles. APC10 also localizes to kinetochores from prophase to anaphase, and to the midbody in ophase and cytokinesis..
此相關標記有：Alexa Fluor 350 標記、Alexa Fluor 488 標記、Alexa Fluor 555 標記、Alexa Fluor 647 標記、AP標記、APC標記、Biotin標記、Cy3標記、Cy5標記、Cy5.5標記、Cy7標記、FITC標記、Gold標記、HRP標記、PE標記、PE-Cy3標記、PE-CY5標記、PE-CY5.5標記、PE-CY7標記、RBITC標記
相關產(chǎn)品：
線粒體脫偶連蛋白1抗體 Anti-UCP-1
植烷酰*羥化酶2相互作用蛋白抗體 Anti-PHYHIP
半乳糖凝集素9抗體 Anti-galectin 9
尿皮質素抗體 Anti-Urocortin
Ⅱ型膠原α1蛋白/軟骨鈣素抗體 Anti-Collagen II/Chondrocalcin
尿皮質素抗體 Anti-Urocortin
核糖核酸結合蛋白2抗體 Anti-PTBP2
*β10抗體 Anti-T Beta 10
神經(jīng)突觸粘附樣分子4抗體 Anti-LRFN3/SALM4
T細胞受體γ抗體 Anti-TCRG
粘附分子IgG樣結構域蛋白2抗體 Anti-AMIGO2
*酶抗體 Anti-Tyrosinase
磷酸化ZCWCC1抗體 Anti-phospho-ZCWCC1(Ser739)
*羥化酶抗體 Anti-Tyk2/TYH
TWIST蛋白抗體 Anti-TWIST protein
ATP結合盒轉運蛋白2抗體 Anti-ABCF2
微管蛋白β3抗體 Anti-Tubb3/Tubulin beta 3
腫瘤抑素抗體 Anti-Tumstatin/COL4A3
鈣結合蛋白5/3抗體 Anti-CABP5/CABP3
微管蛋白γ/Tubulin γ抗體 Anti-gamma tubulin (Centrosome Marker )
高度保守基因相關蛋白Membralin抗體 Anti-Membralin/C19orf6
微管蛋白抗體（免疫組化用抗體）Tubulin β Anti-Tubulin-Beta
*激酶受體A抗體 Anti-TrkA
