Anti-CADPS2抗體,鈣依賴分泌激活蛋白2/自閉癥的相關(guān)蛋白抗體產(chǎn)品詳細(xì)資料
產(chǎn)品編號(hào) BYK-11500R
英文名稱 CADPS2
中文名稱 鈣依賴分泌激活蛋白2/自閉癥的相關(guān)蛋白抗體
別 名 Cadps2; Calcium-dependent activator protein for secretion 2; Calcium-dependent secretion activator 2; CAPS2; CAPS2_HUMAN.
研究領(lǐng)域 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 生長(zhǎng)因子和激素
分 子 量 148kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜
抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產(chǎn)品應(yīng)用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產(chǎn)品應(yīng)用不做依據(jù),具體產(chǎn)品應(yīng)用與實(shí)驗(yàn)稀釋比請(qǐng)!
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
亞 型 IgG
純化方法 affinity purified by Protein G
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Anti-CADPS2抗體,鈣依賴分泌激活蛋白2/自閉癥的相關(guān)蛋白抗體產(chǎn)品介紹
Calcium-dependent secretion activators (CAPS-1 and CAPS-2) are calcium-binding proteins that direct neurotransmitter and neuropeptide-filled vesicles to the cell membrane for secretory granule exocytosis. Both CAPS-1 and CAPS-2 are expressed primarily in the brain where they regulate the secretion of various substances. The CAPS proteins contain a PH domain that is essential for regulation of exocytosis, as well as regulation of phospholipid binding. Through their regulation of neurotrophin release from granule cells, CAPS proteins help to regulate cell fate during neuronal development. CAPS-1 is thought to regulate catecholamine release from neuronal cells, while CAPS-2 is thought to regulate release of both brain-derived neurotrophic factor and neurotrophin-3 from granule cells. Defects in the genes encoding CAPS-1 and CAPS-2 are implicated in impaired cerebral development and autism.
此相關(guān)標(biāo)記有:Alexa Fluor 350 標(biāo)記、Alexa Fluor 488 標(biāo)記、Alexa Fluor 555 標(biāo)記、Alexa Fluor 647 標(biāo)記、AP標(biāo)記、APC標(biāo)記、Biotin標(biāo)記、Cy3標(biāo)記、Cy5標(biāo)記、Cy5.5標(biāo)記、Cy7標(biāo)記、FITC標(biāo)記、Gold標(biāo)記、HRP標(biāo)記、PE標(biāo)記、PE-Cy3標(biāo)記、PE-CY5標(biāo)記、PE-CY5.5標(biāo)記、PE-CY7標(biāo)記、RBITC標(biāo)記
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