Anti-alpha Adaptin/AP1抗體,銜接蛋白α抗體操作步驟產品詳細資料

產品編號 BYK-1228R

英文名稱 alpha Adaptin
中文名稱 銜接蛋白α-Adaptin抗體
別    名 100 kDa coated vesicle protein A; 100 kDa coated vesicle protein C; adaptin alpha A; Adaptin alpha B; Adaptor protein complex AP 2 alpha 1 subunit; Adaptor protein complex AP 2 alpha 2 subunit; Adaptor related protein complex 2 alpha 1 subunit; Adaptor related protein complex 2 alpha 2 subunit; ADTAA; ADTAB; Alpha adaptin A; Alpha adaptin C; AP 2 complex subunit alpha 1; AP 2 complex subunit alpha 2; AP2A2; CLAPA1; CLAPA2; Clathrin assembly protein complex 2 alpha A large chain; Clathrin assembly protein complex 2 alpha C large chain; Clathrin associated/assembly/adaptor protein large alpha 1; Clathrin associated/assembly/adaptor protein large alpha 2; HIP9; Huntingtin interacting protein HYPJ; Huntingtin interacting protein J; HYPJ; KIAA0899; Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit; Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit; AP2A2_HUMAN; AP-2 complex subunit alpha-2; Adapter-related protein complex 2 alpha-2 subunit; Adaptor protein complex AP-2 subunit alpha-2; Alpha-adaptin C; Alpha2-adaptin; Clathrin assembly protein complex 2 alpha-C large chain; Huntingtin yeast partner J; Huntingtin-interacting protein 9; HIP-9; Huntingtin-interacting protein J; Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit.
研究領域 細胞生物  表觀遺傳學  

抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產品應用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產品應用不做依據，具體產品應用與實驗稀釋比請！

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-alpha Adaptin/AP1抗體,銜接蛋白α抗體操作步驟產品介紹 

      Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. 

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