Reagent: in vivo-jetRNA®+ transfection reagent(polyplus RNA脂質(zhì)體轉(zhuǎn)染試劑).
Molecule delivered: mRNA.
Applications: Vaccination / immunization;
Cancer therapy;
in vivo functional studies (Gene expression, CRISPR genome editing).
Targeted organs: All organs (depending on the injection route).
Injection routes: Various administration routes (systemic or local);
Intravenous / intramuscular / intraperitoneal and retro-orbital injections have been successfully tested.
Number of injections in mice: 1 mL is sufficient to perform at least 50 intravenous injections or 100 intramuscular injections in mice.
Storage: Store in vivo-jetRNA®+ at 5 °C ± 3°C. Do not freeze.
Provided with: mRNA buffer.
Highlights:
·Efficient: 100% mRNA encapsulation leading to comparable LNP delivery results;
·Time saving: Ready-to-use reagent that does not require formulation equipment;
·Stable: Maintain liposome size using low to high mRNA concentration over time;
·Universal: Target any organ/tissue using various administration routes;
·Safe: Maintain healthy animals and organs.